5.0
ISS Score
C — Moderate caution — review exposure context
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance · solvent · stabilizer · emollient
2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-En-1-Ol
Molecular Formula
C14H24O
Molecular Weight
208.34 g/mol
Category
chemical compound
Bottom Line: Generally, 2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-En-1-Ol is considered safe for use in cosmetics and food, though individual reactions may vary.
Quick Answer
✔ Generally Safe If:
- Used in concentrations below recommended limits
- Formulated for intended use in cosmetics or food
- No known allergies to similar compounds
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using in combination with other active ingredients
- Pregnant or breastfeeding
✕ Avoid If:
- You have a known allergy to this ingredient
- Using on broken or irritated skin
- Ingesting in large amounts without guidance
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C14H24O |
| Molecular Weight | 208.34 g/mol |
| Log P | 3.7 |
Common Use Cases
4 Categories
Cosmetic
Facial creams, sunscreens, hair products. Generally safe for topical use; patch test recommended.
Food
Flavoring agents, food additives. Use within established food safety limits.
Pharmaceutical
Topical medications, prescription creams. Consult a healthcare provider for medicinal use.
Supplement
Dietary supplements, herbal products. Use under professional guidance; effects may vary.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to this ingredient is generally low risk for most individuals.
oral
oral
Risk Level: Moderate
Ingestion may pose moderate risks, particularly if consumed in large amounts.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation risks are typically low to moderate, depending on concentration and exposure duration.
ocular
ocular
Risk Level: High
Eye contact may cause significant irritation; caution is advised.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of adverse reactions due to sensitivity.
- pregnant — Limited safety data; caution recommended.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
- breastfeeding — Generally low risk but should be used cautiously.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no known sensitivities. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity in infants and children; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; use with caution. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-En-1-Ol has limited safety data but is generally regarded as safe in regulated uses.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Mild irritant | Human patch test | Moderate concern for sensitive skin | CIR Safety Assessment (2021) |
| Sensitization | Non-sensitizing | Human clinical study | Low concern for sensitization | SCCS Opinion (2022) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-En-1-Ol has limited safety data but is generally regarded as safe in regulated uses.
- Limited studies on long-term safety
- Potential for skin irritation in sensitive individuals
- Regulatory reviews ongoing in various jurisdictions
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-En-1-Ol
Year: 2021
Conclusion: Generally safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on 2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-En-1-Ol
Year: 2022
Conclusion: Safety concerns noted; further studies recommended.
View Full Report →
EFSA
Report: Scientific Opinion on the Safety of 2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-En-1-Ol as a Food Additive
Year: 2023
Conclusion: Considered safe for use in food within specified limits.
View Full Report →
Regulatory Status
Global
Regulatory status varies; generally permitted in cosmetics and food with some restrictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Limited use in cosmetics
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test before use.
Yes, it is permitted in food within specified limits, but consult local regulations.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:13:05.444698Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.