6.0
ISS Score
B — Acceptable — low-moderate concern
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
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fragrance ingredient · solvent · emollient
Geranyl Propionate
Molecular Formula
C13H22O2
Molecular Weight
210.31 g/mol
Category
fragrance
Bottom Line: Geranyl Propionate is generally considered safe for use in cosmetics and food, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- not applied to broken skin
- used in well-ventilated areas
- not combined with known allergens
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you have a history of allergies
- you are using other fragrances
✕ Avoid If:
- you are allergic to geranyl compounds
- you have asthma or respiratory issues
- you experience irritation upon use
- you are using on children under 3
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C13H22O2 |
| Molecular Weight | 210.31 g/mol |
| Solubility | 1 ml in 4 ml 80% alcohol (in ethanol) |
| Log P | 3.9 |
Common Use Cases
5 Categories
Cosmetic
Fragrances, lotions, shampoos. Generally safe in cosmetics; patch test recommended.
Food
Flavoring agents, beverages. Used as a flavoring agent; ensure compliance with food safety standards.
Pharmaceutical
Topical creams, ointments. Used in formulations; consult a healthcare provider for concerns.
Household
Air fresheners, cleaning products. Safe for household use; avoid direct inhalation.
Supplement
Dietary supplements. Consult a healthcare professional before use in supplements.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Geranyl Propionate is generally well tolerated on the skin, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of Geranyl Propionate may cause gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and discomfort.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited safety data during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Generally well tolerated with low irritation potential.
- breastfeeding — Use with caution; monitor for effects.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Adults typically have a higher tolerance for cosmetic ingredients. |
| pregnant | Moderate | Limited data on safety during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Geranyl Propionate is assessed for safety in cosmetics and food, showing low toxicity and minimal irritation potential.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | SCCS Opinion (2015) |
| Sensitization | not sensitizing | Human repeated insult patch test | No sensitization observed | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Geranyl Propionate is assessed for safety in cosmetics and food, showing low toxicity and minimal irritation potential.
- Low acute toxicity observed in studies.
- Generally recognized as safe in cosmetics.
- Limited evidence of skin sensitization.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Geranyl Propionate
Year: 2012
Conclusion: Safe for use in cosmetics at concentrations up to 5%.
View Full Report →
SCCS
Report: Opinion on Geranyl Propionate
Year: 2015
Conclusion: Considered safe for use in cosmetic products.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring
Year: 2018
Conclusion: No safety concerns at proposed use levels in food.
View Full Report →
Regulatory Status
Global
Geranyl Propionate is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test before use.
Yes, it is permitted as a flavoring agent in food, but should be used within recommended limits.
Some individuals may experience allergic reactions; discontinue use if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T06:01:35.720914Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.