10.0
ISS Score
A+ — Excellent — very low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · fixative · solvent
Ethylene Brassylate
Molecular Formula
C15H26O4
Molecular Weight
270.36 g/mol
Category
fragrance
Bottom Line: Ethylene Brassylate is generally considered safe for use in cosmetics and household products, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- used in well-formulated products
- applied to intact skin
- used in recommended concentrations
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other fragrance products
✕ Avoid If:
- you have known allergies to fragrances
- you experience irritation upon use
- you are using on broken skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H26O4 |
| Molecular Weight | 270.36 g/mol |
| Boiling Point | 138.0°C |
| Solubility | 1 mL in 1 mL alcohol (in ethanol) |
| Log P | 4.2 |
Common Use Cases
3 Categories
Cosmetic
Perfumes, lotions, shampoos. Generally safe in cosmetic formulations when used as directed.
Household
Air fresheners, cleaning products. Use in well-ventilated areas to minimize inhalation risks.
Pharmaceutical
Topical ointments, creams. Consult a healthcare provider if you have skin sensitivities.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Ethylene Brassylate is generally well tolerated on skin, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of Ethylene Brassylate may cause gastrointestinal discomfort; caution is advised.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may lead to mild respiratory irritation; use in well-ventilated areas.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation; avoid direct exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of skin irritation and systemic effects.
- pregnant — Potential for increased sensitivity to chemical exposures.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- breastfeeding — Generally safe with caution advised.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Adults typically have a higher tolerance for cosmetic ingredients. |
| pregnant | Moderate | Pregnant individuals may have heightened sensitivity to certain chemicals. |
| infants_children | High | Children's skin is more sensitive, increasing risk of irritation. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; caution is advised. |
| sensitive_skin | Moderate | Individuals with sensitive skin may react adversely to this ingredient. |
Toxicology Data
3 Endpoints
Ethylene Brassylate is a fragrance ingredient with low toxicity and is generally safe for use in cosmetics and household products.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | SCCS Opinion (2018) |
| Sensitization | low potential for sensitization | Human patch test | Low concern for sensitization | FDA Regulatory Status (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Ethylene Brassylate is a fragrance ingredient with low toxicity and is generally safe for use in cosmetics and household products.
- Low acute toxicity and non-irritating.
- Used widely in cosmetic formulations.
- Potential for skin sensitization in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Ethylene Brassylate
Year: 2012
Conclusion: Ethylene Brassylate is safe for use in cosmetics at concentrations up to 5%.
View Full Report →
SCCS
Report: Opinion on Ethylene Brassylate
Year: 2018
Conclusion: Ethylene Brassylate is safe for use in cosmetic products.
View Full Report →
FDA
Report: Regulatory Status of Ethylene Brassylate
Year: 2021
Conclusion: Ethylene Brassylate is permitted for use in cosmetics.
View Full Report →
Regulatory Status
Global
Ethylene Brassylate is permitted for use in cosmetics and household products across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should patch test products containing Ethylene Brassylate.
Though rare, some individuals may experience allergic reactions to Ethylene Brassylate. Discontinue use if irritation occurs.
Ethylene Brassylate is commonly found in perfumes, lotions, and household cleaning products.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T05:30:56.045904Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.