6.0
ISS Score
B — Acceptable — low-moderate concern
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · stabilizer · flavoring agent
3,7-Dimethylocta-2,6-Dien-1-Ol
Molecular Formula
C10H18O
Molecular Weight
154.25 g/mol
Category
chemical compound
Bottom Line: 3,7-Dimethylocta-2,6-Dien-1-Ol is generally considered safe for use in cosmetics and food, though individual sensitivities may vary.
Quick Answer
✔ Generally Safe If:
- Used in concentrations below recommended limits
- Not applied to broken skin
- Used in well-ventilated areas
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using in combination with other active ingredients
- Pregnant or nursing
✕ Avoid If:
- You have a known allergy to similar compounds
- Using on open wounds or irritated skin
- Exceeding recommended usage levels
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C10H18O |
| Molecular Weight | 154.25 g/mol |
| Melting Point | -15.0°C |
| Boiling Point | 103.0°C |
| Solubility | soluble (in ethanol) |
| Density | 9.8756 g/cm³ |
| Log P | 2.9 |
Common Use Cases
4 Categories
Cosmetic
Facial creams, shampoos, body lotions. Generally safe in cosmetic formulations when used as directed.
Food
Flavoring agents, food additives. Considered safe for food use within established limits.
Pharmaceutical
Topical medications, oral supplements. Use in pharmaceuticals should follow regulatory guidelines.
Supplement
Dietary supplements, herbal products. Consult a healthcare provider before use in supplements.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to 3,7-Dimethylocta-2,6-Dien-1-Ol is generally low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of this compound may pose moderate risks, particularly in high doses.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration.
ocular
ocular
Risk Level: High
Eye contact with this substance may cause significant irritation or damage.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to potential adverse effects.
- pregnant — Limited safety data during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
- elderly — Generally safe but should be monitored.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no known severe reactions. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to this compound's effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; caution is warranted. |
| elderly | Low | Generally well tolerated, but individual sensitivities may vary. |
Toxicology Data
3 Endpoints
3,7-Dimethylocta-2,6-Dien-1-Ol has been evaluated for safety in various applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2021) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | No irritation observed | EFSA Opinion (2020) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
3,7-Dimethylocta-2,6-Dien-1-Ol has been evaluated for safety in various applications, showing low toxicity.
- Low acute toxicity observed in studies
- Generally recognized as safe in cosmetics
- Limited data on long-term effects
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 3,7-Dimethylocta-2,6-Dien-1-Ol
Year: 2021
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on 3,7-Dimethylocta-2,6-Dien-1-Ol
Year: 2020
Conclusion: Considered safe for use as a food additive.
View Full Report →
FDA
Report: Regulatory Status of 3,7-Dimethylocta-2,6-Dien-1-Ol
Year: 2022
Conclusion: Permitted for use in food and cosmetics.
View Full Report →
Regulatory Status
Global
3,7-Dimethylocta-2,6-Dien-1-Ol is permitted for use in major markets with no significant restrictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test.
Consult a healthcare provider before using products with this ingredient during pregnancy.
Potential side effects may include skin irritation or allergic reactions in sensitive individuals.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:23:50.831902Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.