66.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
preservative · antioxidant · emollient
Amberfleur
Also known as: 7-Acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene, Acetyl hexamethyl tetralin
Trade Names: Amberfleur
Odor: Ambery, musky, powdery, woody
Category
skincare
Bottom Line: Generally, N° Turkish is considered safe for use in cosmetics and food, though individual reactions may vary.
Quick Answer
✔ Generally Safe If:
- used in recommended concentrations
- not combined with known irritants
- applied to intact skin only
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using other active ingredients
- pregnant or nursing
✕ Avoid If:
- you experience irritation or allergic reactions
- you have a known allergy to similar compounds
- using on broken or damaged skin
Chemical Properties
| Property | Value |
|---|
Common Use Cases
4 Categories
Cosmetic
Facial creams, shampoos, body lotions. Generally safe for topical use; patch test recommended.
Food
Flavoring agents, food additives. Generally recognized as safe when used appropriately.
Pharmaceutical
Topical ointments, oral medications. Consult a healthcare professional before use.
Supplement
Dietary supplements, herbal extracts. Use under guidance of a healthcare provider.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure is generally safe with minimal irritation reported.
oral
oral
Risk Level: Moderate
Oral ingestion may pose moderate risks, particularly in high doses.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation risks are typically low, but prolonged exposure should be avoided.
ocular
ocular
Risk Level: High
Ocular exposure can lead to significant irritation and should be avoided.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to ingredients; risk of adverse effects.
- pregnant — Limited data on effects during pregnancy; caution advised.
✔ Well-Tolerated Groups
- general_adult — Generally well tolerated; monitor for any adverse reactions.
- elderly — Generally well tolerated; monitor for any unusual reactions.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; monitor for any adverse reactions. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution advised. |
| infants_children | High | Higher sensitivity to ingredients; risk of adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated; monitor for any unusual reactions. |
Toxicology Data
3 Endpoints
N° Turkish has been evaluated for safety in various applications, showing low toxicity in standard tests.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2021) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | No irritation observed | EFSA Opinion (2020) |
| Sensitization | non-sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
N° Turkish has been evaluated for safety in various applications, showing low toxicity in standard tests.
- Generally safe for cosmetic and food use.
- Low acute toxicity observed in studies.
- No significant adverse effects reported.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of N° Turkish
Year: 2021
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on N° Turkish
Year: 2020
Conclusion: Considered safe for use in food applications.
View Full Report →
FDA
Report: Regulatory Status of N° Turkish
Year: 2022
Conclusion: Permitted for use in food and cosmetics.
View Full Report →
Regulatory Status
Global
N° Turkish is generally permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test.
Yes, it is considered safe for use in food when used as directed.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-19T20:21:36.500794Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.