10.0
ISS Score
A+ — Excellent — very low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
solvent · emollient · stabilizer · fragrance ingredient
Beta-Methyl-Cyclododecaneethanol
Molecular Formula
C15H30O
Molecular Weight
226.40 g/mol
Category
chemical compound
Bottom Line: Beta-Methyl-Cyclododecaneethanol is generally considered safe for use in cosmetics and household products, though caution is advised for sensitive skin.
Quick Answer
✔ Generally Safe If:
- used in recommended concentrations
- applied to intact skin
- not combined with known irritants
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other active ingredients
✕ Avoid If:
- you have a known allergy to similar compounds
- you experience irritation upon use
- you are using on broken skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H30O |
| Molecular Weight | 226.40 g/mol |
| Log P | 6.3 |
Common Use Cases
4 Categories
Cosmetic
Facial creams, shampoos, body lotions. Use in moderation and patch test for sensitivity.
Pharmaceutical
Topical ointments, transdermal patches. Consult a healthcare provider for use in medications.
Household
Cleaning agents, air fresheners. Ensure good ventilation when using household products.
Supplement
Dietary supplements, nutraceuticals. Consult a healthcare professional before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Beta-Methyl-Cyclododecaneethanol is generally well tolerated on skin, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion may lead to gastrointestinal discomfort; limited data on long-term effects.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes may cause significant irritation; caution is advised.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of adverse reactions due to developing systems.
- pregnant — Limited data on safety during pregnancy; use caution.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal side effects.
- elderly — Generally well tolerated, but monitor for sensitivity.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; however, individual sensitivities may vary. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity to chemicals; potential for adverse reactions. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but may have increased sensitivity. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Beta-Methyl-Cyclododecaneethanol has been evaluated for safety in cosmetic and household applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2021) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | No irritation observed | SCCS Opinion (2022) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | FDA Regulatory Review (2023) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Beta-Methyl-Cyclododecaneethanol has been evaluated for safety in cosmetic and household applications, showing low toxicity.
- Low acute toxicity observed in studies.
- Generally safe for topical use.
- Limited data on long-term exposure.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Beta-Methyl-Cyclododecaneethanol
Year: 2021
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on Beta-Methyl-Cyclododecaneethanol
Year: 2022
Conclusion: Considered safe for cosmetic use with restrictions.
View Full Report →
FDA
Report: Regulatory Status of Beta-Methyl-Cyclododecaneethanol
Year: 2023
Conclusion: No restrictions on use in cosmetics and household products.
View Full Report →
Regulatory Status
Global
Beta-Methyl-Cyclododecaneethanol is permitted in the US and UK, with restrictions in the EU. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Use limited to certain concentrations in cosmetics.
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaNO_DATA
No specific data available.
Frequently Asked Questions
While generally safe, it may cause irritation for sensitive skin types.
Consult a healthcare provider before using products with this ingredient during pregnancy.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:27:46.769860Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.