9.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
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Fragrance ingredient · Flavoring agent · Solvent · Fixative
Amyl Cinnamal
Also known as: Amyl Cinnamate, Cinnamyl Amyl Alcohol
Molecular Formula
C14H18O
Molecular Weight
202.29 g/mol
Category
Fragrance
Bottom Line: Amyl Cinnamal is generally considered safe in cosmetics and household products, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- used in low concentrations in cosmetic products
- not applied to broken skin
- used in well-ventilated areas for household products
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in food products for the first time
- exposed to high concentrations in occupational settings
✕ Avoid If:
- you have a known allergy to fragrance ingredients
- using on irritated or damaged skin
- consuming in large amounts in food products
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C14H18O |
| Molecular Weight | 202.29 g/mol |
| Boiling Point | 284.0°C |
| Solubility | miscible (in ethanol) |
| Density | 0.9711 g/cm³ |
| Log P | 4.2 |
Common Use Cases
5 Categories
Cosmetic
Fragrance oils, lotions, shampoos. Generally safe in cosmetics, but may cause irritation in sensitive individuals.
Food
Flavoring agents, baked goods. Use in food is regulated; ensure compliance with local guidelines.
Pharmaceutical
Topical creams, ointments. Use with caution; potential for skin irritation exists.
Household
Air fresheners, cleaning products. Ensure good ventilation when using household products containing this ingredient.
Supplement
Flavoring agents in supplements. Consult a healthcare provider before use in supplements.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Amyl Cinnamal is generally well tolerated on the skin, but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Amyl Cinnamal may lead to gastrointestinal discomfort; caution is advised.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may cause mild respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation; immediate rinsing is recommended.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of irritation and adverse reactions.
- sensitive_skin — Increased likelihood of skin irritation.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- breastfeeding — Generally safe with caution advised.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity to irritants; potential for adverse reactions. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| sensitive_skin | High | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Amyl Cinnamal is a fragrance compound with a history of safe use in cosmetics and food, though some may experience allergic reactions.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Mild irritant | Human patch test | Low concern for irritation | CIR Safety Assessment (2012) |
| Sensitization | Potential sensitizer | Human sensitization study | Moderate concern for sensitization | SCCS Opinion (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Amyl Cinnamal is a fragrance compound with a history of safe use in cosmetics and food, though some may experience allergic reactions.
- Commonly used in fragrances and flavorings.
- Potential for skin sensitization exists.
- Regulatory bodies have assessed its safety.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Amyl Cinnamal
Year: 2012
Conclusion: Amyl Cinnamal is safe for use in cosmetics at concentrations up to 0.5%.
View Full Report →
SCCS
Report: SCCS Opinion on Amyl Cinnamal
Year: 2015
Conclusion: The SCCS considers Amyl Cinnamal safe for use in cosmetics under certain conditions.
View Full Report →
EFSA
Report: Scientific Opinion on Flavouring
Year: 2018
Conclusion: Amyl Cinnamal is acceptable for use as a flavoring substance in food.
View Full Report →
Regulatory Status
Global
Amyl Cinnamal is permitted for use in cosmetics and food across major jurisdictions with specific guidelines. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
Use in cosmetics must comply with SCCS guidelines.
United Kingdom
UK GovernmentPERMITTED
Must comply with UK regulations.
Canada
Health CanadaPERMITTED
Must comply with Health Canada guidelines.
Frequently Asked Questions
Amyl Cinnamal is primarily used as a fragrance in cosmetics and food products.
While generally safe, individuals with sensitive skin may experience irritation; patch testing is advised.
Yes, Amyl Cinnamal can cause allergic reactions in some individuals; caution is recommended.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:12:09.761968Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.