66.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · flavoring agent
BENZENEACETALDEHYDE
Category
fragrance
Bottom Line: Benzeneacetaldehyde is generally considered safe in low concentrations, though its use in certain products may raise concerns.
Quick Answer
✔ Generally Safe If:
- used in well-formulated cosmetic products
- concentrations are kept below regulatory limits
- proper safety assessments have been conducted
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in food products for consumption
- exposed to high concentrations in industrial settings
✕ Avoid If:
- you are pregnant or nursing
- you have a known allergy to similar compounds
- using in products for children
Chemical Properties
| Property | Value |
|---|
Common Use Cases
5 Categories
Cosmetic
Fragrances, lotions, shampoos. Use in cosmetics is generally safe if within recommended limits.
Food
Flavoring agents, beverages. Ensure compliance with food safety regulations.
Pharmaceutical
Topical medications, oral formulations. Use in pharmaceuticals should follow strict safety guidelines.
Household
Cleaning products, air fresheners. Use in household products should be limited to safe concentrations.
Supplement
Dietary supplements. Consult with a healthcare provider before use in supplements.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Benzeneacetaldehyde is generally safe for skin contact in low concentrations.
oral
oral
Risk Level: Moderate
Ingestion of benzeneacetaldehyde may pose moderate risks, especially in high doses.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk but should be minimized in poorly ventilated areas.
ocular
ocular
Risk Level: High
Eye contact with benzeneacetaldehyde can cause irritation and should be avoided.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited data on safety during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated in adults.
- elderly — Generally well tolerated, but monitor for sensitivities.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults, but exposure should be limited. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; caution is recommended. |
| elderly | Low | Generally well tolerated, but individual sensitivities may vary. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Benzeneacetaldehyde has been evaluated for safety in various applications, with mixed findings.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Rabbit - Draize test | Not a skin irritant | CIR Safety Assessment (2015) |
| Sensitization | not sensitizing | Guinea pig - Maximization test | No sensitization observed | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Benzeneacetaldehyde has been evaluated for safety in various applications, with mixed findings.
- Generally recognized as safe in low concentrations.
- Potential irritant at higher levels.
- Regulatory opinions vary by region.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Benzeneacetaldehyde
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 0.1%.
View Full Report →
EFSA
Report: Scientific Opinion on Benzeneacetaldehyde
Year: 2018
Conclusion: Acceptable daily intake established; safe in food applications.
View Full Report →
FDA
Report: Regulatory Status of Benzeneacetaldehyde
Year: 2020
Conclusion: Permitted in cosmetics and food under specific conditions.
View Full Report →
Regulatory Status
Global
Benzeneacetaldehyde is permitted in cosmetics and food across major jurisdictions with specific guidelines. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
Limited to specific concentrations in cosmetics and food.
European Union
European CommissionPERMITTED
Must comply with SCCS recommendations.
United Kingdom
UK GovernmentPERMITTED
Follow EU guidelines post-Brexit.
Canada
Health CanadaPERMITTED
Subject to safety assessments.
Frequently Asked Questions
Generally, benzeneacetaldehyde is safe in cosmetics if used within recommended limits.
Yes, but it must comply with safety regulations and acceptable daily intake levels.
Potential risks include skin irritation and sensitization, especially at high concentrations.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-19T17:58:05.688634Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.