7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · flavoring agent
Trimethylundecenal
Molecular Formula
C14H26O
Molecular Weight
210.36 g/mol
Category
fragrance
Bottom Line: Trimethylundecenal is generally considered safe in cosmetics and household products, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- properly diluted in formulations
- not used in products for children
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in conjunction with other fragrances
- applying to broken or irritated skin
✕ Avoid If:
- you are pregnant or breastfeeding
- you have a known allergy to similar compounds
- using in high concentrations
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C14H26O |
| Molecular Weight | 210.36 g/mol |
| Log P | 5 |
Common Use Cases
5 Categories
Cosmetic
Fragrances, lotions, shampoos. Generally safe in cosmetics when used as directed.
Food
Flavoring agents, food additives. Use in food is limited; ensure compliance with regulations.
Pharmaceutical
Topical creams, ointments. Use cautiously in pharmaceuticals; consult a professional.
Household
Cleaning products, air fresheners. Safe in household products when used as intended.
Supplement
Dietary supplements. Not commonly used in supplements; consult a healthcare provider.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Trimethylundecenal is generally well tolerated on skin, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of Trimethylundecenal may cause gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause mild respiratory irritation.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and discomfort.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of skin irritation and adverse reactions.
- sensitive_skin — Increased likelihood of irritation and allergic reactions.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- elderly — Generally well tolerated, but monitor for sensitivity.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Adults typically have a higher tolerance for cosmetic ingredients. |
| pregnant | Moderate | Pregnant individuals may have heightened sensitivity to certain substances. |
| infants_children | High | Children's skin is more sensitive, increasing irritation risk. |
| breastfeeding | Low to Moderate | Limited data on effects during breastfeeding. |
| elderly | Low | Elderly individuals may have varying skin sensitivities. |
| sensitive_skin | Very High | Individuals with sensitive skin may react adversely. |
Toxicology Data
3 Endpoints
Trimethylundecenal has been evaluated for safety in various applications, showing low toxicity in standard tests.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 2000 mg/kg | Rat - Oral gavage | Moderate acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | Not irritating | CIR Safety Assessment (2015) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Trimethylundecenal has been evaluated for safety in various applications, showing low toxicity in standard tests.
- Low acute toxicity observed in animal studies.
- Generally recognized as safe in cosmetic applications.
- Limited data on food safety; regulatory compliance is essential.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Trimethylundecenal
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 0.5%.
View Full Report →
SCCS
Report: Opinion on Trimethylundecenal
Year: 2018
Conclusion: Considered safe for use in cosmetic products with restrictions.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring
Year: 2017
Conclusion: Insufficient data to establish a safe level for food use.
View Full Report →
Regulatory Status
Global
Trimethylundecenal is permitted in the US and UK, with restrictions in the EU. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Use limited to specific concentrations in cosmetics.
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaNO_DATA
No specific regulations identified.
Frequently Asked Questions
It may cause irritation for some individuals; patch testing is recommended.
Its use in food is limited; ensure compliance with safety regulations.
Possible side effects include skin irritation or allergic reactions in sensitive individuals.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T08:22:34.273985Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.