6.0
ISS Score
C — Moderate caution — review exposure context
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance · solvent · fixative
Methylcyclohexenyl Butanol
Molecular Formula
C11H20O
Molecular Weight
168.28 g/mol
Category
fragrance ingredient
Bottom Line: Methylcyclohexenyl Butanol is generally considered safe in cosmetics and household products, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- used in well-formulated cosmetic products
- applied in recommended concentrations
- not used on broken skin
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using multiple products containing fragrances
- applying to areas with compromised skin
✕ Avoid If:
- you are allergic to fragrance ingredients
- you experience irritation upon use
- you are pregnant or nursing without consulting a doctor
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C11H20O |
| Molecular Weight | 168.28 g/mol |
| Log P | 2.6 |
Common Use Cases
3 Categories
Cosmetic
Perfumes, lotions, shampoos. Generally safe when used as directed in cosmetics.
Household
Air fresheners, cleaning products. Use in well-ventilated areas to minimize inhalation risks.
Pharmaceutical
Topical ointments, creams. Consult a healthcare provider for use in medicinal products.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Methylcyclohexenyl Butanol is generally safe for skin contact, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion may cause gastrointestinal irritation; caution is advised.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: Moderate
Eye contact may cause irritation; flushing with water is recommended if contact occurs.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited safety data during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated in healthy adults.
- elderly — Generally safe but should be monitored.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no significant health issues. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but monitor for sensitivity. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Methylcyclohexenyl Butanol is a fragrance ingredient with moderate safety assessments.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| Skin Irritation | non-irritating | Human Patch Test | Low irritation potential | CIR Safety Assessment (2012) |
| LD50 Oral | Not established | Rat - Oral gavage | Insufficient data for acute toxicity | SCCS Opinion (2015) |
| Sensitization | non-sensitizing | Human Sensitization Test | Low sensitization potential | FDA Regulatory Status (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Methylcyclohexenyl Butanol is a fragrance ingredient with moderate safety assessments.
- Used in cosmetics and household products.
- Generally recognized as safe in regulated concentrations.
- May cause irritation in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Methylcyclohexenyl Butanol
Year: 2012
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
SCCS
Report: Opinion on Methylcyclohexenyl Butanol
Year: 2015
Conclusion: Considered safe for use in cosmetic products.
View Full Report →
FDA
Report: Regulatory Status of Methylcyclohexenyl Butanol
Year: 2021
Conclusion: Permitted for use in cosmetics and household products.
View Full Report →
Regulatory Status
Global
Methylcyclohexenyl Butanol is permitted for use in major jurisdictions with no specific restrictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
None
UK
UK GovernmentPERMITTED
None
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should test products first.
Consult a healthcare provider before using products containing this ingredient during pregnancy.
It is commonly found in perfumes, lotions, and household cleaning products.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T06:43:29.117655Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.