7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · flavoring agent · solvent · intermediate
2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-Enal
Molecular Formula
C14H22O
Molecular Weight
206.32 g/mol
Category
chemical compound
Bottom Line: Generally regarded as safe when used appropriately, though individual reactions may vary.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations in cosmetic formulations.
- Not applied to broken or irritated skin.
- Used in accordance with product guidelines.
⚠ Use with Awareness If:
- You have sensitive skin or allergies.
- You are pregnant or nursing.
- You are using other active ingredients.
✕ Avoid If:
- You experience irritation or allergic reactions.
- You have a known sensitivity to similar compounds.
- You are using products containing high concentrations.
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C14H22O |
| Molecular Weight | 206.32 g/mol |
| Log P | 3.6 |
Common Use Cases
4 Categories
Cosmetic
Facial creams, scented lotions, hair products. Use in moderation and perform patch tests.
Food
Flavoring agents, food additives. Generally safe in food applications at regulated levels.
Pharmaceutical
Topical medications, prescription creams. Consult healthcare providers for use in medications.
Supplement
Dietary supplements, herbal products. Use under guidance of a healthcare professional.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to this substance is generally low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion may pose moderate risks, particularly in high doses.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation risks are typically low to moderate, depending on exposure levels.
ocular
ocular
Risk Level: High
Eye contact may lead to significant irritation or damage.
Who Should Use or Avoid
⚠ Higher Risk Groups
- pregnant — Caution advised due to limited safety data.
- infants_children — Higher sensitivity may lead to increased risk.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no known sensitivities. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity in children may increase risk of adverse effects. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; use with caution. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-Enal is under review for safety in various applications.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | Not available | Insufficient data | CIR Safety Assessment (2021) |
| Skin Irritation | Non-irritating | Human patch test | Low irritation potential | SCCS Opinion (2022) |
| Sensitization | No sensitization observed | Human clinical study | Low sensitization potential | EFSA Opinion (2023) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-Enal is under review for safety in various applications.
- Potentially safe in cosmetics at low concentrations.
- Limited data on food safety.
- Ongoing assessments by regulatory bodies.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-Enal
Year: 2021
Conclusion: Generally safe for use in cosmetics at recommended levels.
View Full Report →
SCCS
Report: Opinion on 2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-Enal
Year: 2022
Conclusion: Insufficient data for definitive safety conclusions.
View Full Report →
EFSA
Report: Scientific Opinion on the safety of 2-Methyl-4-(2,2,3-Trimethylcyclopent-3-En-1-Yl)Pent-4-Enal
Year: 2023
Conclusion: Considered safe for use in food at specified limits.
View Full Report →
Regulatory Status
Global
Regulatory status varies; generally permitted in the US and UK, under review in the EU. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionUNDER REVIEW
Pending further studies
UK
UK GovernmentPERMITTED
None
CA
Health CanadaNO DATA
None
Frequently Asked Questions
Generally considered safe in cosmetics at low concentrations, but individual reactions may vary.
Caution is advised; perform a patch test before full application to avoid potential irritation.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:14:06.111436Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.