9.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · flavoring agent · stabilizer
2,6-Dimethyl-7-Octen-2-Ol
Molecular Formula
C10H20O
Molecular Weight
156.26 g/mol
Category
chemical compound
Bottom Line: 2,6-Dimethyl-7-Octen-2-Ol is generally considered safe in cosmetics and food, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations in cosmetic formulations
- Ingested as part of food flavoring within regulatory limits
- Applied to intact skin without prior irritation
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using in combination with other active ingredients
- Pregnant or nursing women considering supplements
✕ Avoid If:
- You have a known allergy to similar compounds
- Using on broken or irritated skin
- Ingesting in large amounts beyond food flavoring
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C10H20O |
| Molecular Weight | 156.26 g/mol |
| Log P | 2.9 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, lotions, shampoos. Generally safe in cosmetic products when used as directed.
Food
Flavoring agents, beverages. Safe for consumption in regulated amounts.
Pharmaceutical
Topical treatments, medicated creams. Use with caution in sensitive formulations.
Supplement
Dietary supplements, herbal products. Consult a healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to 2,6-Dimethyl-7-Octen-2-Ol is generally well tolerated with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion may cause gastrointestinal irritation; moderate caution is advised.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk but may cause mild respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Eye contact can cause significant irritation; avoid direct exposure to eyes.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposure.
- pregnant — Limited data on safety during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Generally well tolerated with low risk.
- elderly — Typically well tolerated; monitor for reactions.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; monitor for any allergic reactions. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity to chemicals; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated; monitor for any adverse reactions. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
2,6-Dimethyl-7-Octen-2-Ol has been evaluated for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Human patch test | No significant irritation observed | SCCS Opinion (2019) |
| Sensitization | not sensitizing | Human repeated insult patch test | No sensitization potential | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
2,6-Dimethyl-7-Octen-2-Ol has been evaluated for safety in cosmetics and food applications, showing low toxicity.
- Low acute toxicity in animal studies.
- Generally recognized as safe in food applications.
- Limited skin irritation potential.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 2,6-Dimethyl-7-Octen-2-Ol
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
EFSA
Report: Scientific Opinion on 2,6-Dimethyl-7-Octen-2-Ol
Year: 2018
Conclusion: Considered safe for use as a food flavoring substance.
View Full Report →
SCCS
Report: SCCS Opinion on 2,6-Dimethyl-7-Octen-2-Ol
Year: 2019
Conclusion: Safe for use in cosmetic products under specified conditions.
View Full Report →
Regulatory Status
Global
2,6-Dimethyl-7-Octen-2-Ol is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test first.
Yes, it is considered safe for consumption in regulated amounts as a food flavoring.
Generally, it has low toxicity, but allergic reactions may occur in sensitive individuals.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T02:57:43.221904Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.