9.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · fixative · aromatic compound
Cedrol Methyl Ether
Molecular Formula
C16H28O
Molecular Weight
236.39 g/mol
Category
fragrance
Bottom Line: Cedrol Methyl Ether is generally considered safe for use in cosmetics and food, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- applied to intact skin
- not ingested in large amounts
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you have allergies to similar compounds
✕ Avoid If:
- you have a known allergy to cedrol or related compounds
- you are using on broken skin
- you experience irritation or adverse reactions
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C16H28O |
| Molecular Weight | 236.39 g/mol |
| Log P | 4.4 |
Common Use Cases
5 Categories
Cosmetic
Fragrances, lotions, shampoos. Use in moderation to avoid potential skin irritation.
Food
Flavoring agents, beverages. Generally safe when used as a food flavoring.
Pharmaceutical
Topical ointments, medicated creams. Consult a healthcare provider for medicinal use.
Household
Air fresheners, cleaning products. Ensure proper ventilation when using household products.
Supplement
Aromatic oils. Use only as directed and consult a professional.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Cedrol Methyl Ether is generally well tolerated on skin, but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Cedrol Methyl Ether may lead to gastrointestinal discomfort; caution is advised.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but high concentrations may cause respiratory irritation.
ocular
ocular
Risk Level: High
Eye contact with Cedrol Methyl Ether can cause significant irritation; immediate rinsing is recommended.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures may lead to adverse effects.
- pregnant — Limited data necessitates caution during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
- elderly — Generally well tolerated, but monitor for reactions.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally healthy adults can tolerate Cedrol Methyl Ether with minimal risk. |
| pregnant | Moderate | Limited data on the effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; use with caution. |
| elderly | Low | Elderly individuals typically tolerate Cedrol Methyl Ether well. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Cedrol Methyl Ether has been evaluated for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | CIR Safety Assessment (2015) |
| Sensitization | not sensitizing | Human patch test | No sensitization observed | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Cedrol Methyl Ether has been evaluated for safety in cosmetics and food applications, showing low toxicity.
- Low acute toxicity in animal studies.
- Generally recognized as safe in food applications.
- Potential for skin irritation in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Cedrol Methyl Ether
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
EFSA
Report: Scientific Opinion on the safety of Cedrol Methyl Ether
Year: 2018
Conclusion: Considered safe for use as a food flavoring.
View Full Report →
FDA
Report: Food Additive Status
Year: 2020
Conclusion: Generally recognized as safe for food use.
View Full Report →
Regulatory Status
Global
Cedrol Methyl Ether is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test before use.
Yes, it is considered safe for use as a food flavoring agent in regulated amounts.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:39:44.876014Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.