6.0
ISS Score
B — Acceptable — low-moderate concern
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
intermediate · solvent · chemical reagent · potential flavoring agent
Tridec-2-Enenitrile
Molecular Formula
C13H23N
Molecular Weight
193.33 g/mol
Category
chemical compound
Bottom Line: Tridec-2-Enenitrile is generally considered safe for use in cosmetics and household products, though caution is advised in food applications.
Quick Answer
✔ Generally Safe If:
- used in well-formulated cosmetic products
- concentrations are within regulatory limits
- properly labeled for consumer use
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in food products without proper guidance
- applying in large quantities
✕ Avoid If:
- you are pregnant or nursing
- you have known allergies to similar compounds
- using in unregulated food products
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C13H23N |
| Molecular Weight | 193.33 g/mol |
| Log P | 5.6 |
Common Use Cases
5 Categories
Cosmetic
Facial creams, sunscreens, hair conditioners. Generally safe in cosmetic formulations when used as directed.
Food
Food flavorings, preservatives. Use with caution; regulatory status may vary.
Pharmaceutical
Topical medications, transdermal patches. Safety in pharmaceuticals is under review; consult a professional.
Household
Cleaning agents, air fresheners. Safe for household use when used as directed.
Supplement
Dietary supplements. Not widely used in supplements; consult a healthcare provider.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Tridec-2-Enenitrile shows low dermal irritation potential based on available studies.
oral
oral
Risk Level: Moderate
Ingestion may pose moderate risks, including gastrointestinal irritation.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may lead to respiratory irritation, but risks are generally low.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and potential damage.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk due to developing systems and potential for adverse reactions.
- pregnant — Caution advised due to limited data on safety during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
- elderly — Generally well tolerated, but individual monitoring is recommended.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity to chemicals; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but monitor for sensitivities. |
Toxicology Data
3 Endpoints
Tridec-2-Enenitrile has been evaluated for safety in cosmetics and food applications, with varying conclusions.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2021) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | Not irritating | CIR Safety Assessment (2021) |
| Sensitization | not sensitizing | Guinea pig - Maximization test | No sensitization observed | CIR Safety Assessment (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Tridec-2-Enenitrile has been evaluated for safety in cosmetics and food applications, with varying conclusions.
- Safety assessments indicate moderate concern in food use.
- Cosmetic use is generally supported by safety reviews.
- Regulatory status is inconsistent across jurisdictions.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Tridec-2-Enenitrile
Year: 2021
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on Tridec-2-Enenitrile
Year: 2020
Conclusion: Insufficient data to support safe use in food applications.
View Full Report →
FDA
Report: Regulatory Status of Tridec-2-Enenitrile
Year: 2022
Conclusion: No specific regulations; general safety guidelines apply.
View Full Report →
Regulatory Status
Global
Regulatory status varies; generally safe in cosmetics but under review for food use. Switch to Detailed mode for full regulatory breakdown.
United States
FDANO SPECIFIC REGULATIONS
General safety guidelines apply.
European Union
European CommissionUNDER REVIEW FOR FOOD USE
Pending further safety data.
United Kingdom
UK GovernmentNO SPECIFIC REGULATIONS
General safety guidelines apply.
Canada
Health CanadaNO SPECIFIC REGULATIONS
General safety guidelines apply.
Frequently Asked Questions
Generally, yes, when used in recommended concentrations as per safety assessments.
Caution is advised; perform a patch test before full application.
Use with caution; its safety in food applications is still under review.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T08:13:25.797860Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.