8.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
flavoring agent · fragrance ingredient · solvent · chemical intermediate
Ethyl Decadienoate
Molecular Formula
C12H20O2
Molecular Weight
196.29 g/mol
Category
chemical compound
Bottom Line: Ethyl Decadienoate is generally considered safe for use in cosmetics and food, though individual sensitivities may vary.
Quick Answer
✔ Generally Safe If:
- used in concentrations below 1%
- applied to intact skin
- not combined with known irritants
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other active ingredients
✕ Avoid If:
- you have a known allergy to similar compounds
- you experience irritation or allergic reactions
- you are using on broken skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C12H20O2 |
| Molecular Weight | 196.29 g/mol |
| Boiling Point | 70.0°C |
| Solubility | soluble (in ethanol) |
| Log P | 4 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, skin creams, lotions. Generally safe in cosmetic products when used as directed.
Food
Flavoring agents, food preservatives. Considered safe for food use in regulated amounts.
Pharmaceutical
Topical medications, preservatives in formulations. Use with caution in pharmaceutical applications.
Supplement
Dietary supplements, nutraceuticals. Limited use; consult a healthcare provider.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Ethyl Decadienoate is generally well tolerated on skin, but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Ethyl Decadienoate may lead to gastrointestinal discomfort; caution is advised.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation; immediate rinsing is recommended.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of irritation and adverse reactions.
- pregnant — Limited safety data; consult healthcare provider.
✔ Well-Tolerated Groups
- general_adult — Generally well tolerated with minimal risk.
- breastfeeding — Low to moderate risk; consult if concerned.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity to chemicals; potential for adverse reactions. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Ethyl Decadienoate has been evaluated for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | No irritation observed | CIR Safety Assessment (2015) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Ethyl Decadienoate has been evaluated for safety in cosmetics and food applications, showing low toxicity.
- Low acute toxicity in animal studies.
- Generally recognized as safe in food applications.
- Limited data on long-term effects.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Ethyl Decadienoate
Year: 2015
Conclusion: Ethyl Decadienoate is safe for use in cosmetics at concentrations up to 1%.
View Full Report →
EFSA
Report: Scientific Opinion on Ethyl Decadienoate
Year: 2018
Conclusion: Considered safe for use as a food flavoring agent.
View Full Report →
FDA
Report: Food Additive Status
Year: 2020
Conclusion: Ethyl Decadienoate is permitted as a food additive.
View Full Report →
Regulatory Status
Global
Ethyl Decadienoate is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
Ethyl Decadienoate may cause irritation in sensitive individuals; patch testing is recommended.
Consult a healthcare provider before using products containing Ethyl Decadienoate during pregnancy.
It is used for its fragrance and preservative properties in cosmetic formulations.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T05:30:04.647046Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.