5.0
ISS Score
C — Moderate caution — review exposure context
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · stabilizer · intermediate
Amylvinyl Carbinol
Molecular Formula
C8H16O
Molecular Weight
128.21 g/mol
Category
chemical compound
Bottom Line: Amylvinyl Carbinol is generally considered safe for use in cosmetics and food, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- used in recommended concentrations
- not applied to broken skin
- used in well-ventilated areas
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in combination with other fragrances
- exposed to high temperatures during use
✕ Avoid If:
- you are pregnant or nursing
- you have a known allergy to similar compounds
- using on open wounds or irritated skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C8H16O |
| Molecular Weight | 128.21 g/mol |
| Melting Point | 175.0°C |
| Boiling Point | 84.0°C |
| Solubility | Miscible at room temperature (in ethanol) |
| Log P | 2.6 |
Common Use Cases
5 Categories
Cosmetic
Fragrances, lotions, shampoos. Use in moderation to avoid skin irritation.
Food
Flavoring agents, beverages. Generally safe in food applications at low concentrations.
Pharmaceutical
Topical creams, medicated ointments. Consult a healthcare provider for use in medications.
Household
Cleaning products, air fresheners. Ensure good ventilation when using household products.
Supplement
Dietary supplements. Consult a doctor before using in supplements.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Amylvinyl Carbinol is generally well tolerated on skin, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion may cause gastrointestinal discomfort; use caution with dosages.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but high concentrations may irritate respiratory tract.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation; avoid direct exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk due to sensitivity to chemical exposure.
- pregnant — Limited safety data; use with caution.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
- elderly — Generally safe but should be monitored.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; monitor for any adverse reactions. |
| pregnant | Moderate | Limited data on safety during pregnancy; use with caution. |
| infants_children | High | Higher sensitivity to chemicals; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data; potential for transfer through milk. |
| elderly | Low | Generally well tolerated; monitor for sensitivity. |
Toxicology Data
3 Endpoints
Amylvinyl Carbinol has been assessed for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | Not a skin irritant | CIR Safety Assessment (2015) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Amylvinyl Carbinol has been assessed for safety in cosmetics and food applications, showing low toxicity.
- Low acute toxicity in animal studies.
- Generally recognized as safe in food applications.
- Potential for skin irritation in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Amylvinyl Carbinol
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
EFSA
Report: Scientific Opinion on Amylvinyl Carbinol
Year: 2018
Conclusion: Considered safe for use as a food flavoring agent.
View Full Report →
FDA
Report: Food Additive Status
Year: 2020
Conclusion: Generally recognized as safe when used appropriately.
View Full Report →
Regulatory Status
Global
Amylvinyl Carbinol is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
None
UK
UK GovernmentPERMITTED
None
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
It is commonly used as a fragrance in cosmetics and as a flavoring agent in food products.
While generally safe, individuals with sensitive skin should perform a patch test before use.
Yes, it is recognized as safe for use in food flavoring at low concentrations.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:14:11.311749Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.