4.0
ISS Score
D — Higher caution — limited safety data
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance · solvent · stabilizer · intermediate
1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene
Molecular Formula
C15H24
Molecular Weight
204.35 g/mol
Category
chemical compound
Bottom Line: 1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene is generally considered safe in cosmetics and supplements, though caution is advised based on individual sensitivities.
Quick Answer
✔ Generally Safe If:
- Used in recommended concentrations
- Not combined with known irritants
- Skin tested prior to widespread use
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using other active ingredients in products
- Pregnant or nursing
✕ Avoid If:
- You have a known allergy to similar compounds
- Experiencing skin irritation or reactions
- Using on broken or compromised skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H24 |
| Molecular Weight | 204.35 g/mol |
| Log P | 4.5 |
Common Use Cases
3 Categories
Cosmetic
Facial creams, hair styling products, body lotions. Use in moderation and perform patch tests.
Pharmaceutical
Topical ointments, prescription creams. Consult a healthcare provider before use.
Supplement
Energy boosters, dietary pills. Follow dosage instructions carefully.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to 1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene is generally low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion may pose moderate risks due to potential toxicity and limited data on effects.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration and duration.
ocular
ocular
Risk Level: High
Eye contact may result in significant irritation or damage, indicating a high risk.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity may lead to increased risk of adverse effects.
- pregnant — Limited data necessitates caution during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Generally well tolerated with minimal risk.
- elderly — May tolerate with monitoring for adverse effects.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no known severe reactions. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | Very High | Higher sensitivity in children may lead to increased risk of adverse effects. |
| breastfeeding | Insufficient Data | Insufficient data on safety during breastfeeding; caution is warranted. |
| elderly | Low to Moderate | Elderly may have varied responses; monitor for adverse effects. |
Toxicology Data
3 Endpoints
Research indicates that 1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene is generally safe for topical use, though data on oral consumption is limited.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Mildly irritating | Rabbit - Draize test | Moderate irritation potential | CIR Safety Assessment (2021) |
| Sensitization | Not sensitizing | Guinea pig - Maximization test | Low sensitization potential | SCCS Opinion (2022) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Research indicates that 1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene is generally safe for topical use, though data on oral consumption is limited.
- Limited studies on long-term safety
- Potential for skin irritation
- Regulatory reviews ongoing
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene
Year: 2021
Conclusion: Generally safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on 1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene
Year: 2022
Conclusion: Insufficient data to fully assess safety in cosmetics.
View Full Report →
FDA
Report: Regulatory Status of 1,3-Dimethyl-8-Propan-2-Yltricyclo[4.4.0.02,7]Dec-3-Ene
Year: 2023
Conclusion: No specific regulations; generally recognized as safe in cosmetics.
View Full Report →
Regulatory Status
Global
Regulatory status varies; generally permitted in the US and UK, under review in the EU. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionUNDER REVIEW
Pending further studies
UK
UK GovernmentPERMITTED
None
CA
Health CanadaNO DATA
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform patch tests before use.
Consult with a healthcare provider before using products with this ingredient during pregnancy.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T02:29:29.907489Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.