7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · emollient · stabilizer
Heptamethyl Decahydroindenofuran
Molecular Formula
C18H32O
Molecular Weight
264.4 g/mol
Category
synthetic compound
Bottom Line: Heptamethyl Decahydroindenofuran is generally considered safe in cosmetics and household products, though caution is advised for sensitive skin.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- applied to intact skin
- formulated in products with stabilizers
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using multiple products with similar ingredients
✕ Avoid If:
- you have known allergies to similar compounds
- you experience irritation or adverse reactions
- you are using on broken or damaged skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C18H32O |
| Molecular Weight | 264.4 g/mol |
| Log P | 5.3 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, lotions, shampoos. Generally safe for topical use in cosmetics.
Pharmaceutical
Topical ointments, creams. Use with caution in medicinal products.
Household
Cleaning agents, air fresheners. Ensure proper ventilation when using household products.
Supplement
Dietary supplements. Limited data on safety in supplements.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Heptamethyl Decahydroindenofuran is generally low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of Heptamethyl Decahydroindenofuran poses moderate risks, particularly in large amounts.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration and duration.
ocular
ocular
Risk Level: Moderate
Eye contact with Heptamethyl Decahydroindenofuran can cause moderate irritation.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposure may lead to adverse effects.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
- elderly — Generally well tolerated, but individual health factors should be considered.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no significant health issues. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposure. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; caution is advised. |
| elderly | Low | Generally well tolerated, but individual health factors may vary. |
Toxicology Data
3 Endpoints
Heptamethyl Decahydroindenofuran has limited safety data, primarily used in cosmetics and household products.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Non-irritating | Human patch test | Low irritation potential | CIR Safety Assessment (2021) |
| Sensitization | Not sensitizing | Human clinical study | No sensitization observed | SCCS Opinion (2022) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Heptamethyl Decahydroindenofuran has limited safety data, primarily used in cosmetics and household products.
- Limited assessments available.
- Primarily used in cosmetic formulations.
- Safety data suggests low toxicity.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Heptamethyl Decahydroindenofuran
Year: 2021
Conclusion: Generally safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on Heptamethyl Decahydroindenofuran
Year: 2022
Conclusion: Safety concerns noted for sensitive populations.
View Full Report →
FDA
Report: Regulatory Status of Heptamethyl Decahydroindenofuran
Year: 2023
Conclusion: No specific regulations; generally recognized as safe in cosmetics.
View Full Report →
Regulatory Status
Global
Regulatory status varies; permitted in the US and UK, restricted in the EU. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Use limited to cosmetics only
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaNO_DATA
No specific regulations identified
Frequently Asked Questions
It is a synthetic compound used primarily in cosmetics and household products.
Caution is advised for sensitive skin; patch testing is recommended.
Currently, there is no established safety data for food use.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T06:04:43.004749Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.