Verdyl Acetate — Ingredient Safety Profile | HumanSafe™
10.0
ISS Score
A+ — Excellent — very low hazard
Higher = Safer
Environmental
(ESS)
Confidence
(CSS)
Fragrance ingredient · Solvent · Flavoring agent

Verdyl Acetate

CAS No.: 5413-60-5  ·  INCI: VERDYL ACETATE  ·  Updated: 2026-04-13
Molecular Formula
C12H16O2
Molecular Weight
192.25 g/mol
Category
Fragrance

Bottom Line: Verdyl Acetate is generally considered safe for use in cosmetics and food, though caution is advised for sensitive individuals.

Natural aroma Pleasant scent Flavor enhancer CAS 5413-60-5
Quick Answer

✔ Generally Safe If:

  • used in low concentrations
  • applied to intact skin
  • not combined with known irritants

⚠ Use with Awareness If:

  • you have sensitive skin
  • you are pregnant or nursing
  • you are using other fragrances

✕ Avoid If:

  • you have a known allergy to fragrances
  • you experience irritation or allergic reactions
  • you are using on broken skin
Chemical Properties
PropertyValue
Molecular FormulaC12H16O2
Molecular Weight192.25 g/mol
Log P2.2
Common Use Cases
4 Categories
Cosmetic
Perfumes, lotions, shampoos. Generally safe in cosmetics; patch test recommended.
Food
Flavoring agents, beverages. Used in food flavoring; ensure compliance with local regulations.
Pharmaceutical
Topical creams, ointments. Use in pharmaceuticals is limited; consult a healthcare provider.
Supplement
Flavoring in dietary supplements. Check for allergies; use as directed.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Verdyl Acetate is generally well tolerated with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of Verdyl Acetate may pose moderate risks, including potential gastrointestinal irritation.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Eye contact with Verdyl Acetate can cause significant irritation and should be avoided.
Who Should Use or Avoid
⚠ Higher Risk Groups
  • infants_children — Higher risk due to developing systems and potential for greater sensitivity.
  • pregnant — Increased sensitivity may affect safety during pregnancy.
✔ Well-Tolerated Groups
  • general_adult — Typically well tolerated with low risk of adverse effects.
  • elderly — Generally well tolerated, but monitoring is advised.
Population-Specific Safety Data
PopulationRisk LevelConsiderations
general_adultLowAdults typically have a higher tolerance for exposure to Verdyl Acetate.
pregnantModeratePregnant individuals may have increased sensitivity to certain chemicals.
infants_childrenHighChildren are more vulnerable to chemical exposures due to their developing systems.
breastfeedingLow to ModerateLimited data on transfer through breast milk; caution is advised.
elderlyLowElderly individuals may have varying sensitivities to chemicals.
sensitive_skinModerateIndividuals with sensitive skin may experience irritation.
Toxicology Data
3 Endpoints

Verdyl Acetate has been assessed for safety in cosmetics and food applications, showing low toxicity.

EndpointValueTest MethodInterpretationSource
LD50 Oral 5000 mg/kg Rat - Oral gavage Low acute toxicity CIR Safety Assessment (2015)
Skin Irritation non-irritating Rabbit - Dermal application No irritation observed CIR Safety Assessment (2015)
Sensitization not sensitizing Guinea Pig - Maximization Test No sensitization observed CIR Safety Assessment (2015)
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments

Verdyl Acetate has been assessed for safety in cosmetics and food applications, showing low toxicity.

  • Low acute toxicity in animal studies.
  • Generally recognized as safe in cosmetics.
  • Limited data on long-term effects.

Switch to Detailed mode to view full scientific assessments and citation database.

CIR
Report: Safety Assessment of Fragrance Ingredients
Year: 2015
Conclusion: Safe for use in cosmetics at typical concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on Flavouring Substances
Year: 2018
Conclusion: Considered safe for use in food flavoring.
View Full Report →
FDA
Report: Food Additive Status List
Year: 2021
Conclusion: No specific restrictions; generally recognized as safe.
View Full Report →
Regulatory Status
Global

Verdyl Acetate is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.

United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test before use.
Consult a healthcare provider before using products containing Verdyl Acetate if pregnant.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
VersionDateISS ScoreWhat Changed
1.0.0 - Initial enrichment 2026-04-13T08:28:39.407639Z Initial data enrichment via 3-phase structured outputs
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.