7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · emollient
Ethyl Ethyldimethylcyclohexene-1-Carboxylate
Molecular Formula
C13H22O2
Molecular Weight
210.31 g/mol
Category
chemical compound
Bottom Line: Ethyl Ethyldimethylcyclohexene-1-Carboxylate is generally considered safe for use in cosmetics and food, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- applied to intact skin
- not combined with known irritants
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other active ingredients
✕ Avoid If:
- you have a known allergy to similar compounds
- you experience irritation upon use
- you are using on broken skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C13H22O2 |
| Molecular Weight | 210.31 g/mol |
| Log P | 3.4 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, skin creams, lotions. Use in moderation and patch test for sensitivity.
Food
Flavoring agents, food additives. Generally recognized as safe when used appropriately.
Pharmaceutical
Topical medications, transdermal patches. Consult a healthcare provider for use in medications.
Supplement
Dietary supplements, herbal products. Use under guidance of a healthcare professional.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Ethyl Ethyldimethylcyclohexene-1-Carboxylate is generally considered low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of this substance may pose moderate risks, particularly in large amounts.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration and duration.
ocular
ocular
Risk Level: High
Eye contact with this substance can cause significant irritation and is considered high risk.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited data necessitates caution.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
- elderly — Generally well tolerated, but monitor for sensitivities.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but age-related sensitivities may apply. |
Toxicology Data
3 Endpoints
Ethyl Ethyldimethylcyclohexene-1-Carboxylate has been evaluated for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2021) |
| Skin Irritation | non-irritating | Rabbit - Draize test | No irritation observed | EFSA Opinion (2020) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Ethyl Ethyldimethylcyclohexene-1-Carboxylate has been evaluated for safety in cosmetics and food applications, showing low toxicity.
- Low acute toxicity observed in studies.
- Generally safe for cosmetic use.
- Limited data on long-term effects.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Ethyl Ethyldimethylcyclohexene-1-Carboxylate
Year: 2021
Conclusion: Safe for use in cosmetics at concentrations up to 5%.
View Full Report →
EFSA
Report: Scientific Opinion on Ethyl Ethyldimethylcyclohexene-1-Carboxylate
Year: 2020
Conclusion: Considered safe as a food flavoring agent.
View Full Report →
FDA
Report: Food Additive Status
Year: 2022
Conclusion: Permitted for use in food products under specified conditions.
View Full Report →
Regulatory Status
Global
Ethyl Ethyldimethylcyclohexene-1-Carboxylate is generally permitted across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
Use in food and cosmetics under specified conditions.
European Union
European CommissionPERMITTED
Allowed in cosmetics and food flavorings.
United Kingdom
UK GovernmentPERMITTED
Regulated similarly to EU standards.
Canada
Health CanadaPERMITTED
Allowed in cosmetics and food products.
Frequently Asked Questions
While generally safe, individuals with sensitive skin should patch test before use.
Yes, it is permitted as a flavoring agent in food under specific conditions.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T05:32:35.712274Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.