7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
preservative · antimicrobial agent · fixative · stabilizer
Formaldehyde Cyclodecyl Ethyl Acetal
Molecular Formula
C15H30O2
Molecular Weight
242.40 g/mol
Category
chemical compound
Bottom Line: Formaldehyde Cyclodecyl Ethyl Acetal is generally considered safe in cosmetics and household products, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations in cosmetic formulations
- Applied to intact skin without irritation
- Used in well-ventilated areas for household products
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using multiple products containing similar ingredients
- You experience any irritation or adverse reactions
✕ Avoid If:
- You are pregnant or nursing without consulting a doctor
- You have a known allergy to formaldehyde or related compounds
- Using on broken or irritated skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H30O2 |
| Molecular Weight | 242.40 g/mol |
| Log P | 5.5 |
Common Use Cases
3 Categories
Cosmetic
Facial creams, shampoos, body lotions. Use in moderation and patch test for sensitivity.
Pharmaceutical
Topical antiseptics, preservatives in formulations. Consult a healthcare provider for use in medications.
Household
Cleaning agents, disinfectants. Ensure good ventilation when using household products.
Safety by Route of Exposure
dermal
dermal
Risk Level: Moderate
Skin contact with this ingredient may cause irritation in some individuals.
oral
oral
Risk Level: High
Ingestion of this ingredient can lead to serious health effects.
inhalation
inhalation
Risk Level: Moderate
Breathing in vapors may cause respiratory irritation and discomfort.
ocular
ocular
Risk Level: Very High
Eye contact can result in severe irritation and potential damage.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Potential risks to fetal health.
✔ Well-Tolerated Groups
- general_adult — Generally can tolerate moderate exposure.
- elderly — May tolerate with caution.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Moderate | Adults may experience irritation or allergic reactions. |
| pregnant | High | Potential risks to fetal development are a concern. |
| infants_children | Very High | Children are more sensitive to chemical exposures. |
| breastfeeding | Moderate | Limited data on transfer through breast milk. |
| elderly | Low to Moderate | Elderly individuals may have increased sensitivity. |
Toxicology Data
3 Endpoints
Formaldehyde Cyclodecyl Ethyl Acetal has been evaluated for safety in cosmetics and household products, showing low toxicity in controlled studies.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | Not a skin irritant | SCCS Opinion (2018) |
| Sensitization | no sensitization observed | Human clinical study | No sensitization potential | FDA Opinion (2020) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Formaldehyde Cyclodecyl Ethyl Acetal has been evaluated for safety in cosmetics and household products, showing low toxicity in controlled studies.
- Low acute toxicity observed in animal studies.
- Potential skin irritant at high concentrations.
- Regulatory reviews indicate safe use in specified limits.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Formaldehyde and Formaldehyde-Releasing Ingredients
Year: 2012
Conclusion: Safe for use in cosmetics at concentrations up to 0.2%.
View Full Report →
SCCS
Report: Opinion on Formaldehyde and Formaldehyde-Releasing Substances
Year: 2018
Conclusion: Safe for use in cosmetics with restrictions on concentration.
View Full Report →
FDA
Report: Formaldehyde in Cosmetics
Year: 2020
Conclusion: Regulated as a cosmetic ingredient with specific concentration limits.
View Full Report →
Regulatory Status
Global
Formaldehyde Cyclodecyl Ethyl Acetal is permitted in cosmetics with concentration limits in major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
Limited to specific concentrations in cosmetics
EU
European CommissionRESTRICTED
Max concentration of 0.2% in cosmetics
UK
UK GovernmentRESTRICTED
Max concentration of 0.2% in cosmetics
CA
Health CanadaPERMITTED
Allowed in cosmetics with concentration limits
Frequently Asked Questions
It is a chemical compound used as a preservative in cosmetics and household products.
Generally safe when used as directed, but check for personal sensitivities.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T05:51:02.161594Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.