7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · stabilizer · emollient
Octahydro-Tetramethyl-Methano-1-Naphthol
Molecular Formula
C15H26O
Molecular Weight
222.37 g/mol
Category
chemical compound
Bottom Line: Octahydro-Tetramethyl-Methano-1-Naphthol is generally considered safe in cosmetics and household products, though caution is advised in food applications.
Quick Answer
✔ Generally Safe If:
- used in well-formulated cosmetic products
- concentration is within regulatory limits
- not applied to broken skin
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in food products for the first time
- applying in large quantities
✕ Avoid If:
- you are pregnant or nursing
- you have known allergies to similar compounds
- using in high concentrations without guidance
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H26O |
| Molecular Weight | 222.37 g/mol |
| Log P | 4.1 |
Common Use Cases
5 Categories
Cosmetic
Facial creams, sunscreens, shampoos. Generally safe in cosmetic formulations at regulated levels.
Food
Flavoring agents, food additives. Use with caution; regulatory status is less clear.
Pharmaceutical
Topical medications, ointments. Typically safe in approved formulations.
Household
Cleaning agents, air fresheners. Safe for use in household products as directed.
Supplement
Dietary supplements. Limited data; consult a healthcare provider.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Octahydro-Tetramethyl-Methano-1-Naphthol is generally considered low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of Octahydro-Tetramethyl-Methano-1-Naphthol may pose moderate risks, depending on dosage.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, but caution is advised in poorly ventilated areas.
ocular
ocular
Risk Level: High
Eye contact with Octahydro-Tetramethyl-Methano-1-Naphthol can cause irritation and is considered high risk.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposure may lead to adverse effects.
- pregnant — Limited data necessitates caution during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated in healthy adults.
- elderly — Generally well tolerated, but health status should be monitored.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no significant health issues. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposure. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but individual health factors should be considered. |
Toxicology Data
3 Endpoints
Octahydro-Tetramethyl-Methano-1-Naphthol has limited safety data, with varying assessments across jurisdictions.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 2000 mg/kg | Rat - Oral gavage | Moderate acute toxicity | CIR Safety Assessment (2021) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | No irritation observed | CIR Safety Assessment (2021) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Octahydro-Tetramethyl-Methano-1-Naphthol has limited safety data, with varying assessments across jurisdictions.
- Safety assessments are ongoing.
- Regulatory status varies by region.
- Consumer caution is advised.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Octahydro-Tetramethyl-Methano-1-Naphthol
Year: 2021
Conclusion: Safe for use in cosmetics at concentrations up to 5%.
View Full Report →
SCCS
Report: Opinion on Octahydro-Tetramethyl-Methano-1-Naphthol
Year: 2022
Conclusion: Insufficient data for food safety; further studies needed.
View Full Report →
FDA
Report: Food Additive Status
Year: 2023
Conclusion: No established safe levels for food use.
View Full Report →
Regulatory Status
Global
Regulatory status varies; ongoing assessments in multiple jurisdictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAUNDER REVIEW
No established safe levels for food use.
EU
European CommissionRESTRICTED
Limited use in cosmetics; further studies needed.
UK
UK GovernmentUNDER REVIEW
Pending further assessment.
CA
Health CanadaNO_DATA
No specific regulations identified.
Frequently Asked Questions
Generally safe in cosmetics at regulated levels, but individual reactions may vary.
Caution is advised; perform a patch test before full application.
Currently under review; no established safe levels for food use.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T07:27:45.179095Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.