7.0
ISS Score
B — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
emollient · solvent · thickening agent · skin conditioning agent
C10-11 Isoparaffin
Category
petroleum-derived hydrocarbon
Bottom Line: C10-11 Isoparaffin is generally considered safe for use in cosmetics and household products, though some individuals may experience sensitivity.
Quick Answer
✔ Generally Safe If:
- used in well-formulated products
- applied to intact skin
- used in recommended concentrations
⚠ Use with Awareness If:
- you have sensitive skin
- you are using multiple products with similar ingredients
- you experience irritation after use
✕ Avoid If:
- you have known allergies to hydrocarbons
- you are pregnant or nursing without consulting a doctor
- you have open wounds or broken skin
Chemical Properties
| Property | Value |
|---|---|
| Solubility | insoluble in water |
Common Use Cases
3 Categories
Cosmetic
Moisturizers, sunscreens, makeup removers. Generally safe for topical use; patch test recommended.
Pharmaceutical
Topical ointments, creams. Use as directed; consult a healthcare provider if unsure.
Household
Cleaning agents, air fresheners. Follow usage instructions; ensure good ventilation.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
C10-11 Isoparaffin is generally well tolerated on skin with low irritation potential.
oral
oral
Risk Level: Insufficient Data
Limited data on oral toxicity; ingestion should be avoided.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may cause mild respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: Moderate
Contact with eyes may cause irritation; rinsing is recommended.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of skin irritation and sensitivity.
- sensitive_skin — Increased likelihood of adverse reactions.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with low irritation potential.
- breastfeeding — Generally safe with minimal absorption.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; minimal risk of skin irritation. |
| pregnant | Low to Moderate | Limited data on effects during pregnancy; caution advised. |
| infants_children | Moderate | Higher sensitivity in young skin; use with care. |
| breastfeeding | Low | Minimal systemic absorption expected; generally safe. |
| elderly | Low to Moderate | Skin may be more sensitive; monitor for irritation. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
C10-11 Isoparaffin is a petroleum-derived hydrocarbon with low toxicity and is commonly used in cosmetics and household products.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | >5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Rabbit - Dermal application | No irritation observed | SCCS Opinion (2015) |
| Sensitization | non-sensitizing | Guinea Pig - Maximization test | No sensitization observed | FDA Regulatory Status (2020) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
C10-11 Isoparaffin is a petroleum-derived hydrocarbon with low toxicity and is commonly used in cosmetics and household products.
- Low toxicity profile in various studies.
- Generally recognized as safe in cosmetic formulations.
- Potential for skin irritation in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of C10-11 Isoparaffin
Year: 2012
Conclusion: C10-11 Isoparaffin is safe for use in cosmetics at concentrations up to 50%.
View Full Report →
SCCS
Report: Opinion on C10-11 Isoparaffin
Year: 2015
Conclusion: Considered safe for use in cosmetic products.
View Full Report →
FDA
Report: Regulatory Status of C10-11 Isoparaffin
Year: 2020
Conclusion: Generally recognized as safe for use in cosmetics.
View Full Report →
Regulatory Status
Global
C10-11 Isoparaffin is permitted for use in cosmetics across major jurisdictions with no specific restrictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should patch test before use.
Though rare, some individuals may experience allergic reactions; discontinue use if irritation occurs.
It is commonly found in moisturizers, sunscreens, and household cleaning products.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:34:17.642341Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.