8.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
solvent · fragrance ingredient · stabilizer · emollient
Pentamethylcyclopent-3-Ene-Butanol
Molecular Formula
C14H26O
Molecular Weight
210.36 g/mol
Category
chemical compound
Bottom Line: Pentamethylcyclopent-3-Ene-Butanol is generally considered safe for use in cosmetics and household products, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- Used in accordance with product guidelines
- Not applied to broken skin
- Used in well-ventilated areas
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using in combination with other active ingredients
- Pregnant or nursing
✕ Avoid If:
- You have known allergies to similar compounds
- Using on open wounds or irritated skin
- Ingesting or using inappropriately
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C14H26O |
| Molecular Weight | 210.36 g/mol |
| Log P | 3.9 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, skin creams, lotions. Generally safe for topical use; patch test recommended.
Pharmaceutical
Topical ointments, medicated creams. Use under medical supervision; potential for irritation.
Household
Cleaning agents, air fresheners. Ensure good ventilation during use.
Supplement
Dietary supplements. Consult healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Pentamethylcyclopent-3-ene-butanol is generally safe for skin contact but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of pentamethylcyclopent-3-ene-butanol may lead to gastrointestinal discomfort and should be avoided.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may cause respiratory irritation; use in well-ventilated areas is advisable.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation; protective eyewear is recommended during use.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity and risk of adverse effects.
- pregnant — Limited data; caution advised during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
- elderly — Generally well tolerated, but monitor for sensitivities.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity in young children; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but age-related sensitivities may apply. |
Toxicology Data
3 Endpoints
Pentamethylcyclopent-3-Ene-Butanol has limited safety data, primarily used in cosmetics and household products.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Mild irritant | Human patch test | Low concern for irritation | CIR Safety Assessment (2021) |
| Sensitization | Non-sensitizing | Human clinical study | Low concern for sensitization | SCCS Opinion (2022) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Pentamethylcyclopent-3-Ene-Butanol has limited safety data, primarily used in cosmetics and household products.
- Limited toxicological data available.
- Generally recognized as safe in cosmetic formulations.
- Potential for skin irritation in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Pentamethylcyclopent-3-Ene-Butanol
Year: 2021
Conclusion: Safe for use in cosmetics at concentrations up to 5%.
View Full Report →
SCCS
Report: Opinion on Pentamethylcyclopent-3-Ene-Butanol
Year: 2022
Conclusion: Considered safe for cosmetic use with restrictions.
View Full Report →
FDA
Report: Regulatory Status of Pentamethylcyclopent-3-Ene-Butanol
Year: 2023
Conclusion: No specific regulations; generally recognized as safe in cosmetics.
View Full Report →
Regulatory Status
Global
Pentamethylcyclopent-3-Ene-Butanol is permitted in the US and UK, restricted in the EU. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Use limited to cosmetic products only.
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaNO DATA
None
Frequently Asked Questions
It may cause irritation in sensitive individuals; patch testing is recommended.
Consult your healthcare provider before using products with this ingredient during pregnancy.
Potential side effects include skin irritation or allergic reactions in some individuals.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T07:35:07.246145Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.