6.0
ISS Score
B — Acceptable — low-moderate concern
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · flavoring agent · solvent · stabilizer
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol
Molecular Formula
C14H24O
Molecular Weight
208.34 g/mol
Category
chemical compound
Bottom Line: 3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol is generally considered safe in cosmetics and food, though caution is advised when used in sensitive applications.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- formulated for topical application
- not used on broken skin
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other active ingredients
✕ Avoid If:
- you have known allergies to similar compounds
- you experience irritation or adverse reactions
- you are using it in high concentrations
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C14H24O |
| Molecular Weight | 208.34 g/mol |
| Solubility | Soluble (in ethanol) |
| Log P | 3.3 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, skin creams, lotions. Use in low concentrations to minimize irritation risk.
Food
Flavoring agents, food additives. Generally recognized as safe when used appropriately.
Pharmaceutical
Topical medications, therapeutic creams. Consult a healthcare provider for use in medications.
Supplement
Dietary supplements, herbal products. Use with caution; consult a healthcare professional.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to this ingredient is generally considered low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion may pose moderate risks, particularly in high doses or sensitive individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration and duration.
ocular
ocular
Risk Level: Insufficient Data
Limited data on ocular exposure makes risk assessment challenging.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher susceptibility to adverse effects due to developing systems.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- elderly — Generally low risk but should be monitored.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no known allergies. |
| pregnant | Moderate | Pregnant individuals may have heightened sensitivity to certain substances. |
| infants_children | High | Children may be more susceptible to adverse effects due to their developing systems. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; caution is advised. |
| elderly | Low | Elderly individuals may have varying sensitivities; monitor closely. |
Toxicology Data
3 Endpoints
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol has limited safety data, primarily used in cosmetics and food.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2021) |
| Skin Irritation | Mildly irritating | Human patch test | Moderate concern for sensitive skin | SCCS Opinion (2022) |
| Sensitization | Not sensitizing | Human sensitization study | Low concern for sensitization | EFSA Opinion (2023) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol has limited safety data, primarily used in cosmetics and food.
- Limited assessments available.
- Potential for skin irritation.
- Regulatory status varies by jurisdiction.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol
Year: 2021
Conclusion: Generally safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on 3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol
Year: 2022
Conclusion: Safety concerns noted for sensitive skin types.
View Full Report →
EFSA
Report: Scientific Opinion on 3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol
Year: 2023
Conclusion: Considered safe for use as a food flavoring agent.
View Full Report →
Regulatory Status
Global
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol is permitted in major jurisdictions with no significant restrictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, it may cause irritation in sensitive skin types. Patch testing is recommended.
Consult a healthcare provider before using products with this ingredient during pregnancy.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:27:44.454261Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.