6.0
ISS Score
B — Acceptable — low-moderate concern
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance · flavoring agent · aromatic compound · solvent
2,4-Dimethyl-3-Cyclohexene Carboxaldehyde
Molecular Formula
C9H14O
Molecular Weight
138.21 g/mol
Category
fragrance ingredient
Bottom Line: 2,4-Dimethyl-3-Cyclohexene Carboxaldehyde is generally considered safe in cosmetics and food, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations in cosmetic formulations
- Ingested in food products within regulatory limits
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- You are pregnant or nursing
✕ Avoid If:
- You have a known allergy to fragrance ingredients
- You are using products on broken skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C9H14O |
| Molecular Weight | 138.21 g/mol |
| Log P | 1.4 |
Common Use Cases
5 Categories
Cosmetic
Perfumes, lotions, shampoos. Generally safe in cosmetic products at low concentrations.
Food
Flavoring agents, beverages. Used as a flavoring agent within safe limits.
Pharmaceutical
Topical creams, ointments. Used in formulations, but check for allergies.
Household
Air fresheners, cleaning products. Safe in household products, avoid direct skin contact.
Supplement
Dietary supplements. Consult a healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to 2,4-Dimethyl-3-Cyclohexene Carboxaldehyde is generally low risk, but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of this compound may pose moderate risks, including potential gastrointestinal irritation.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, with potential for respiratory irritation in high concentrations.
ocular
ocular
Risk Level: Moderate
Eye contact may cause moderate irritation; precautions should be taken to avoid exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures may lead to adverse effects.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated by adults, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; use with caution. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
2,4-Dimethyl-3-Cyclohexene Carboxaldehyde is a fragrance ingredient with moderate safety assessments.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | Non-irritating | Rabbit - Dermal application | Not a skin irritant | SCCS Opinion (2015) |
| Sensitization | Not sensitizing | Guinea Pig - Maximization test | No sensitization observed | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
2,4-Dimethyl-3-Cyclohexene Carboxaldehyde is a fragrance ingredient with moderate safety assessments.
- Used in cosmetics and food flavoring
- Moderate safety profile based on assessments
- Caution advised for sensitive individuals
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Fragrance Ingredients
Year: 2012
Conclusion: Generally safe for use in cosmetics at low concentrations.
View Full Report →
SCCS
Report: Opinion on Fragrance Ingredients
Year: 2015
Conclusion: Safety concerns for high concentrations; otherwise acceptable.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring
Year: 2018
Conclusion: Considered safe for use in food flavoring within limits.
View Full Report →
Regulatory Status
Global
2,4-Dimethyl-3-Cyclohexene Carboxaldehyde is permitted in major jurisdictions with no significant restrictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
None
UK
UK GovernmentPERMITTED
None
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
It may cause irritation for some individuals; patch testing is recommended.
Consult your healthcare provider before using products with this ingredient during pregnancy.
Potential side effects include skin irritation or allergic reactions in sensitive individuals.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T02:51:22.165585Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.