7.0
ISS Score
B — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance · fixative · solvent · aromatic compound
Vetiverol
Also known as: Vetiver alcohol, Vetiverol, Vetiverol acetate
Molecular Formula
C15H24O
Molecular Weight
220.35 g/mol
Category
fragrance ingredient
Bottom Line: Vetiverol is generally considered safe for use in cosmetics and food, though individual sensitivities may occur.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- properly diluted in formulations
- not applied to broken skin
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other fragrance products
✕ Avoid If:
- you have a known allergy to vetiver or related compounds
- you experience irritation upon use
- you are using on children without consultation
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C15H24O |
| Molecular Weight | 220.35 g/mol |
| Solubility | Soluble (in ethanol) |
| Log P | 3 |
Common Use Cases
5 Categories
Cosmetic
Perfumes, lotions, soaps. Generally safe in cosmetics when used as directed.
Food
Flavoring agents, beverages. Considered safe for food use in regulated amounts.
Pharmaceutical
Topical ointments, medicated creams. Use with caution in medicinal products.
Household
Air fresheners, cleaning products. Safe for household use when properly formulated.
Supplement
Herbal supplements. Consult a healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Vetiverol is generally well tolerated on the skin, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of Vetiverol may cause gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and discomfort.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to potential irritants.
- pregnant — Limited safety data during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with low risk.
- elderly — Generally well tolerated, but monitor for reactions.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Adults typically have a higher tolerance for Vetiverol exposure. |
| pregnant | Moderate | Limited data on the effects of Vetiverol during pregnancy. |
| infants_children | Very High | Children may be more sensitive to the effects of Vetiverol. |
| breastfeeding | Low to Moderate | Limited data on the safety of Vetiverol in breastfeeding women. |
| elderly | Low | Elderly individuals generally tolerate Vetiverol well. |
Toxicology Data
3 Endpoints
Vetiverol is a fragrance ingredient with a moderate safety profile, though some individuals may experience sensitivities.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | SCCS Opinion (2015) |
| Sensitization | not sensitizing | Human sensitization study | No sensitization observed | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Vetiverol is a fragrance ingredient with a moderate safety profile, though some individuals may experience sensitivities.
- Commonly used in cosmetics and food products.
- Potential for allergic reactions in sensitive individuals.
- Regulatory assessments support its safe use.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Vetiver Oil
Year: 2012
Conclusion: Safe for use in cosmetics at concentrations up to 5%.
View Full Report →
SCCS
Report: Opinion on Vetiver Oil
Year: 2015
Conclusion: Considered safe for use in cosmetic products.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring
Year: 2018
Conclusion: Safe for use in food flavoring applications.
View Full Report →
Regulatory Status
Global
Vetiverol is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
Vetiverol may cause irritation in sensitive individuals; patch testing is recommended.
Consult a healthcare provider before using products with Vetiverol during pregnancy.
Yes, Vetiverol is permitted in food flavoring under EU and FDA regulations.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T08:31:18.335981Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.