4.0
ISS Score
D — Higher caution — limited safety data
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance agent · skin conditioning agent · antioxidant · anti-inflammatory
Acetylated Vetiveria Zizanioides Root Oil
Category
essential oil
Bottom Line: Generally regarded as safe for topical use, though some may experience sensitivity. Typically used in cosmetics and food, based on current evidence.
Quick Answer
✔ Generally Safe If:
- Used in diluted form for topical applications
- Ingested in small amounts as a flavoring agent
- Conducted patch tests prior to widespread use
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- You are pregnant or nursing
- You are taking other medications or supplements
✕ Avoid If:
- You have a known allergy to vetiver or related plants
- You experience irritation or adverse reactions
- You are using it in high concentrations without guidance
Chemical Properties
| Property | Value |
|---|
Common Use Cases
4 Categories
Cosmetic
Fragrances, skin creams, soaps. Generally safe for topical use when diluted properly.
Food
Flavoring agents, beverages. Safe in small amounts; consult guidelines for use.
Pharmaceutical
Topical ointments, aromatherapy products. Use with caution; potential for skin sensitivity.
Supplement
Herbal supplements, essential oil capsules. Consult a healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Acetylated Vetiveria Zizanioides Root Oil is generally well tolerated with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of Acetylated Vetiveria Zizanioides Root Oil may pose moderate risks, including potential gastrointestinal upset.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause mild respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Eye contact with Acetylated Vetiveria Zizanioides Root Oil can cause significant irritation and discomfort.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity and risk of adverse effects.
- pregnant — Limited safety data; potential risks should be evaluated.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with low risk.
- sensitive_skin — May tolerate with caution; patch testing recommended.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no significant health issues. |
| pregnant | Moderate | Limited data on safety during pregnancy; potential risks should be considered. |
| infants_children | Very High | Higher sensitivity in infants and children; potential for adverse effects. |
| breastfeeding | Moderate | Limited data on excretion in breast milk; caution is advised. |
| sensitive_skin | High | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Acetylated Vetiveria Zizanioides Root Oil is generally safe for use in cosmetics and food, though some individuals may experience sensitivity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Non-irritating | Human patch test | Low concern for irritation | CIR Safety Assessment (2021) |
| Sensitization | No sensitization observed | Human clinical study | Low concern for sensitization | SCCS Opinion (2022) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Acetylated Vetiveria Zizanioides Root Oil is generally safe for use in cosmetics and food, though some individuals may experience sensitivity.
- Used in various cosmetic and food products
- Potential for skin irritation in sensitive individuals
- Regulatory assessments indicate moderate safety
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Acetylated Vetiveria Zizanioides Root Oil
Year: 2021
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on Acetylated Vetiveria Zizanioides Root Oil
Year: 2022
Conclusion: Considered safe for cosmetic use with restrictions on concentration.
View Full Report →
EFSA
Report: Scientific Opinion on Acetylated Vetiveria Zizanioides Root Oil
Year: 2023
Conclusion: Safe for use as a food flavoring agent within specified limits.
View Full Report →
Regulatory Status
Global
Regulatory status varies; generally permitted with some restrictions in cosmetics. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED WITH RESTRICTIONS
Max concentration of 0.5% in cosmetics
UK
UK GovernmentPERMITTED WITH RESTRICTIONS
Max concentration of 0.5% in cosmetics
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
Generally safe for skin use when diluted, but patch testing is recommended.
It can be ingested in small amounts as a flavoring, but consult guidelines first.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:55:01.335268Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.