9.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · masking agent · odorant · sensory enhancer
Octahydro-8,8-Dimethyl-2-Naphthaldehyde
Molecular Formula
C13H20O
Molecular Weight
192.30 g/mol
Category
fragrance
Bottom Line: Octahydro-8,8-Dimethyl-2-Naphthaldehyde is generally considered safe in cosmetics and household products, though caution is advised for sensitive individuals.
Quick Answer
✔ Generally Safe If:
- used in low concentrations
- properly diluted in formulations
- not applied to broken skin
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in conjunction with other fragrances
- applying to children or infants
✕ Avoid If:
- you are pregnant or nursing
- you have a known allergy to similar compounds
- using in high concentrations
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C13H20O |
| Molecular Weight | 192.30 g/mol |
| Log P | 2.6 |
Common Use Cases
5 Categories
Cosmetic
Perfumes, lotions, shampoos. Generally safe in cosmetic formulations when used appropriately.
Food
Flavoring agents, food additives. Use in food is regulated; ensure compliance with local laws.
Pharmaceutical
Topical creams, ointments. Consult a healthcare provider for use in medicinal products.
Household
Air fresheners, cleaning products. Use in well-ventilated areas to minimize inhalation risks.
Supplement
Aromatic supplements. Consult a healthcare professional before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Octahydro-8,8-Dimethyl-2-Naphthaldehyde is generally well tolerated on skin but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of this compound may lead to gastrointestinal discomfort; caution is advised.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may cause respiratory irritation; use in well-ventilated areas.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation; avoid direct exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited data on safety during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
- elderly — Generally low to moderate risk, but monitor closely.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally healthy adults may tolerate this compound well with minimal risk. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | Very High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low to Moderate | Elderly individuals may have varying sensitivities. |
Toxicology Data
3 Endpoints
Octahydro-8,8-Dimethyl-2-Naphthaldehyde has been evaluated for safety in various applications, showing low toxicity in standard tests.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Rabbit - Draize test | No irritation observed | SCCS Opinion (2018) |
| Sensitization | not sensitizing | Guinea Pig - Maximization test | No sensitization observed | EFSA Opinion (2019) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Octahydro-8,8-Dimethyl-2-Naphthaldehyde has been evaluated for safety in various applications, showing low toxicity in standard tests.
- Low acute toxicity observed in animal studies.
- Generally recognized as safe in cosmetic use.
- Limited data on food safety; regulatory compliance required.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Fragrance Ingredients
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
SCCS
Report: Opinion on Fragrance Ingredients
Year: 2018
Conclusion: Safe for use in cosmetics with specified restrictions.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring
Year: 2019
Conclusion: Considered safe for use in food flavoring under specific conditions.
View Full Report →
Regulatory Status
Global
Octahydro-8,8-Dimethyl-2-Naphthaldehyde is permitted in cosmetics and food, with some restrictions in the EU. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Use limited to cosmetic products only.
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
It may cause irritation in sensitive individuals; patch testing is recommended.
It's best to avoid using products with this ingredient during pregnancy due to limited safety data.
In the EU, its use is restricted to cosmetics; check local regulations for other uses.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T07:24:25.735388Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.