AQUA — Ingredient Safety Profile | HumanSafe™
72.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
Higher = Safer
Environmental
(ESS)
Confidence
(CSS)
solvent · humectant · diluent · carrier

AQUA

CAS No.: 7732-18-5  ·  INCI: AQUA  ·  Updated: 2026-04-19
Category
solvent

Bottom Line: Aqua is generally considered safe for use in various products, though its quality can vary based on source and treatment.

hydrating natural essential versatile CAS 7732-18-5
Quick Answer

✔ Generally Safe If:

  • used in regulated cosmetic and food products
  • purified and treated to remove contaminants
  • used in appropriate concentrations

⚠ Use with Awareness If:

  • you have sensitive skin or allergies
  • the product is used in high concentrations
  • the source of water is unclear

✕ Avoid If:

  • the product is unregulated or from unknown sources
  • you have a known allergy to water contaminants
  • the product shows signs of contamination
Chemical Properties
PropertyValue
Solubilitysoluble in water
Common Use Cases
6 Categories
Cosmetic
Facial creams, shampoos, lotions. Ensure products are from reputable brands.
Food
Beverages, soups, sauces. Use only in products that meet food safety standards.
Pharmaceutical
Injectable solutions, oral medications. Purity is critical for injectable forms.
Household
Cleaning solutions, detergents. Follow usage instructions carefully.
Supplement
Hydration powders, nutritional drinks. Check for quality certifications.
Veterinary
Pet shampoos, oral solutions. Ensure products are specifically formulated for pets.
Safety by Route of Exposure
dermal
dermal
Risk Level: Very Low
Aqua is generally safe for skin contact and is a common ingredient in cosmetics.
oral
oral
Risk Level: Very Low
Aqua is typically safe for ingestion as it is water, a vital component of food and beverages.
inhalation
inhalation
Risk Level: Low
Inhalation of aerosolized water is generally safe, but excessive exposure may cause irritation.
ocular
ocular
Risk Level: Low
Aqua is typically safe for eye contact, but may cause mild irritation in sensitive individuals.
Who Should Use or Avoid
⚠ Higher Risk Groups
  • sensitive_skin — Individuals with sensitive skin may react to certain formulations.
✔ Well-Tolerated Groups
  • general_adult — Generally well tolerated by adults in various applications.
  • pregnant — Considered safe for use during pregnancy.
  • infants_children — Typically safe for infants and children in appropriate products.
  • breastfeeding — Safe for breastfeeding mothers and their infants.
  • elderly — Well tolerated by elderly individuals.
Population-Specific Safety Data
PopulationRisk LevelConsiderations
general_adultVery LowAdults generally tolerate Aqua well in various forms.
pregnantVery LowAqua poses no known risks during pregnancy when used appropriately.
infants_childrenVery LowInfants and children typically tolerate Aqua well in food and cosmetics.
breastfeedingVery LowAqua is safe for breastfeeding mothers and their infants.
elderlyVery LowElderly individuals generally tolerate Aqua without issues.
sensitive_skinLowIndividuals with sensitive skin may experience mild irritation.
Toxicology Data
3 Endpoints

Aqua is widely used as a solvent in various industries, with safety assessments indicating low toxicity.

EndpointValueTest MethodInterpretationSource
LD50 Oral Not applicable Not toxic CIR Safety Assessment (2012)
Skin Irritation non-irritating Human patch test No irritation observed CIR Safety Assessment (2012)
Sensitization non-sensitizing Human patch test No sensitization observed CIR Safety Assessment (2012)
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments

Aqua is widely used as a solvent in various industries, with safety assessments indicating low toxicity.

  • Commonly used in cosmetics and food products.
  • Generally recognized as safe when purified.
  • Regulatory bodies monitor its use.

Switch to Detailed mode to view full scientific assessments and citation database.

CIR
Report: Safety Assessment of Water
Year: 2012
Conclusion: Water is safe for use in cosmetics.
View Full Report →
EFSA
Report: Scientific Opinion on Water Quality
Year: 2016
Conclusion: Water used in food is safe if treated properly.
View Full Report →
FDA
Report: Food Additives and Ingredients
Year: 2020
Conclusion: Water is generally recognized as safe.
View Full Report →
Regulatory Status
Global

Aqua is permitted for use across major jurisdictions with no significant restrictions. Switch to Detailed mode for full regulatory breakdown.

United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
Aqua is generally safe, but those with sensitive skin should test products first.
Yes, Aqua is permitted in food products when treated and purified.
Risks are minimal if Aqua is sourced and treated properly; contamination is a concern.
Version History
Audit Trail
VersionDateISS ScoreWhat Changed
1.0.0 - Initial enrichment 2026-04-19T17:33:15.428335Z Initial data enrichment via 3-phase structured outputs
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.