Linalool — Ingredient Safety Profile | HumanSafe™
7.0
ISS Score
A- — Good — low to minimal hazard
Higher = Safer
Environmental
(ESS)
Confidence
(CSS)
Fragrance · Solvent

Linalool

CAS No.: 78-70-6  ·  INCI: LINALOOL  ·  Updated: 2023-10-01
Also known as: 3,7-dimethyl-1,6-octadien-3-ol, linalyl alcohol
Molecular Formula
C10H18O
Category
Fragrance

Bottom Line: Linalool is generally considered safe for use in cosmetics, though individual sensitivities may occur.

Natural Plant-derived CAS 78-70-6
Quick Answer

✔ Generally Safe If:

  • Used in low concentrations in formulations
  • Not applied to broken skin
  • Formulated for intended use

⚠ Use with Awareness If:

  • You have sensitive skin
  • You are prone to allergies
  • You are using other fragrance products

✕ Avoid If:

  • You have known allergies to linalool
  • You experience irritation upon use
  • You are using on sensitive areas
Chemical Properties
PropertyValue
Molecular FormulaC10H18O
SolubilitySoluble in alcohol and oils, slightly soluble in water
Common Use Cases
1 Categories
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to linalool is generally considered low risk, though some individuals may experience irritation or allergic reactions.
oral
oral
Risk Level: Insufficient Data
Oral safety data for linalool is limited. Ingestion may lead to gastrointestinal discomfort in some cases.
inhalation
inhalation
Risk Level: Low
Inhalation of linalool in fragrance products is generally considered safe, though high concentrations may cause respiratory irritation.
ocular
ocular
Risk Level: Insufficient Data
Ocular exposure to linalool may cause irritation. Data on long-term effects is insufficient.
Who Should Use or Avoid
⚠ Higher Risk Groups
  • Pregnant Individuals — Limited data on safety during pregnancy.
  • Infants and Children — Safety data for infants and children is limited.
✔ Well-Tolerated Groups
  • General Adult Population — Generally well tolerated with low risk of irritation.
Population-Specific Safety Data
PopulationRisk LevelConsiderations
General Adult PopulationLowGenerally well tolerated in adults, though individual sensitivities may vary.
Pregnant IndividualsInsufficient DataLimited data on the safety of linalool during pregnancy.
Infants and ChildrenInsufficient DataSafety data for infants and children is limited.
Toxicology Data
0 Endpoints

Linalool is commonly used in cosmetics and fragrances, with a generally low risk profile. However, individual sensitivities may occur.

EndpointValueTest MethodInterpretationSource
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments

Linalool is commonly used in cosmetics and fragrances, with a generally low risk profile. However, individual sensitivities may occur.

  • Natural fragrance ingredient
  • Potential allergen for some individuals
  • Widely used in personal care products

Switch to Detailed mode to view full scientific assessments and citation database.

Pending formal assessment
Report: No formal safety assessment identified
Year: 2026
Conclusion: This ingredient has not been formally assessed by major regulatory or scientific bodies based on available records.
Regulatory Status
Global

Regulatory restrictions apply in some jurisdictions. Must be labeled if >0.001% (leave-on) or >0.01% (rinse-off) Switch to Detailed mode for full regulatory breakdown.

European Union
European CommissionFRAGRANCE ALLERGEN - MANDATORY LABELING REQUIRED
Must be labeled if >0.001% (leave-on) or >0.01% (rinse-off)
United States
FDAPERMITTED; GRAS FOR FOOD FLAVORING
Frequently Asked Questions
Linalool is primarily used as a fragrance ingredient in cosmetics and personal care products.
While many people tolerate linalool well, those with sensitive skin may experience irritation. A patch test is recommended.
Yes, linalool can be a potential allergen for some individuals, leading to skin irritation or allergic reactions.
Version History
Audit Trail
VersionDateISS ScoreWhat Changed
2023-10-01
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.