9.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · flavoring agent
2-Benzylideneheptanal
Molecular Formula
C14H18O
Molecular Weight
202.29 g/mol
Category
fragrance
Bottom Line: Generally regarded as safe in low concentrations, though some individuals may experience sensitivities when used in cosmetics or food products.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations
- Not applied to broken skin
- Used in well-ventilated areas
- Formulated by reputable manufacturers
⚠ Use with Awareness If:
- You have sensitive skin
- You are pregnant or nursing
- You are using other fragrance products
- You have a history of allergies
✕ Avoid If:
- You have known allergies to fragrances
- You experience irritation or discomfort
- You are using on children
- You have respiratory issues
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C14H18O |
| Molecular Weight | 202.29 g/mol |
| Log P | 4.2 |
Common Use Cases
4 Categories
Cosmetic
Perfumes, lotions, soaps. Use in moderation to avoid skin irritation.
Food
Flavoring agents, beverages. Generally safe in food at regulated levels.
Pharmaceutical
Topical medications, ointments. Consult a healthcare provider for use in medications.
Supplement
Dietary supplements. Limited use; consult a professional before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to 2-Benzylideneheptanal is generally low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of 2-Benzylideneheptanal may pose moderate risks, particularly in high doses.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration and duration.
ocular
ocular
Risk Level: High
Eye contact with 2-Benzylideneheptanal can cause irritation and is considered high risk.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposure.
- pregnant — Limited data on safety during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with proper use.
- elderly — Generally well tolerated, but monitor for reactions.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no known severe reactions. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposure. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; caution is recommended. |
| elderly | Low | Generally well tolerated, but individual sensitivities may vary. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
4 Endpoints
2-Benzylideneheptanal has been evaluated for safety in cosmetics and food applications, showing low toxicity in studies.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | >5000 mg/kg | Rat - Oral | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | Non-irritating | Human patch test | No irritation observed | SCCS Opinion (2018) |
| Sensitization | Not sensitizing | Human repeated insult patch test | No sensitization observed | EFSA Opinion (2017) |
| Eye Irritation | Mild irritation | Rabbit - Eye | Mild irritant | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
2-Benzylideneheptanal has been evaluated for safety in cosmetics and food applications, showing low toxicity in studies.
- Low acute toxicity reported
- Potential skin irritant
- Used in various consumer products
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 2-Benzylideneheptanal
Year: 2015
Conclusion: Considered safe for use in cosmetics at concentrations up to 0.5%.
View Full Report →
SCCS
Report: Opinion on 2-Benzylideneheptanal
Year: 2018
Conclusion: Safe for use in cosmetic products with restrictions on concentration.
View Full Report →
EFSA
Report: Scientific Opinion on 2-Benzylideneheptanal
Year: 2017
Conclusion: Acceptable daily intake established; safe for food use.
View Full Report →
Regulatory Status
Global
Regulatory status varies; generally permitted with some restrictions in cosmetics. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Max 0.5% in cosmetics
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
It may cause irritation in sensitive individuals; patch testing is recommended.
Consult a healthcare provider before using products with this ingredient during pregnancy.
Possible side effects include skin irritation and allergic reactions in some users.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:00:42.354586Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.