9.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance · flavoring agent · aroma compound
Allyl Alpha-Ionone
Molecular Weight
134.19 g/mol
Category
fragrance ingredient
Bottom Line: Allyl Alpha-Ionone is generally considered safe in cosmetics and food, though some individuals may experience sensitivities.
Quick Answer
✔ Generally Safe If:
- used in low concentrations in cosmetics
- included in food products within regulatory limits
- not applied to broken skin
- not used by individuals with known allergies to similar compounds
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or nursing
- you are using other fragrance products
- you experience irritation after use
✕ Avoid If:
- you have a known allergy to Allyl Alpha-Ionone
- you are using it in high concentrations
- you have a history of skin reactions to fragrances
- you are applying it to mucous membranes
Chemical Properties
| Property | Value |
|---|---|
| Molecular Weight | 134.19 g/mol |
Common Use Cases
3 Categories
Cosmetic
Perfumes, lotions, shampoos. Use in low concentrations to minimize irritation risk.
Food
Flavoring agents, beverages. Generally safe when used within established limits.
Supplement
Dietary supplements with flavoring. Consult a healthcare provider if unsure about use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Allyl Alpha-Ionone is generally well tolerated on skin, but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Allyl Alpha-Ionone may lead to gastrointestinal discomfort; use caution.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation; avoid direct exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of irritation and adverse effects.
- pregnant — Limited safety data; use with caution.
✔ Well-Tolerated Groups
- general_adult — Generally well tolerated with minimal risk.
- breastfeeding — Low to moderate risk; consult healthcare provider.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; use with caution. |
| infants_children | High | Higher sensitivity in young children; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use cautiously. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Allyl Alpha-Ionone is assessed for safety in cosmetics and food, showing low toxicity and minimal irritation potential.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | SCCS Opinion (2018) |
| Sensitization | not sensitizing | Human sensitization study | No sensitization reactions | EFSA Opinion (2017) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Allyl Alpha-Ionone is assessed for safety in cosmetics and food, showing low toxicity and minimal irritation potential.
- Low acute toxicity in animal studies.
- Generally recognized as safe in food applications.
- Potential for skin irritation in sensitive individuals.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Allyl Alpha-Ionone
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 0.5%.
View Full Report →
SCCS
Report: Opinion on Allyl Alpha-Ionone
Year: 2018
Conclusion: Considered safe for use in cosmetics with appropriate restrictions.
View Full Report →
EFSA
Report: Scientific Opinion on Flavoring
Year: 2017
Conclusion: Safe for use as a flavoring substance in food.
View Full Report →
Regulatory Status
Global
Allyl Alpha-Ionone is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
Use in cosmetics must comply with SCCS recommendations.
UK
UK GovernmentPERMITTED
Must comply with UK regulations.
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin may experience irritation.
Consult a healthcare provider before using products with this ingredient during pregnancy.
Possible side effects include skin irritation or allergic reactions in sensitive individuals.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T04:00:00.085508Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.