66.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance agent · skin conditioning agent · antimicrobial agent · aromatic agent
Citrus Aurantium Bergamia Peel Oil
Also known as: Bergamot Oil, Bergamot Peel Oil
Category
essential oil
Bottom Line: Citrus Aurantium Bergamia Peel Oil is generally considered safe for use in cosmetics and food, though some individuals may experience sensitivity.
Quick Answer
✔ Generally Safe If:
- used in diluted form in cosmetics
- consumed in small amounts as a flavoring agent
- not applied to broken skin
- used by individuals without citrus allergies
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or breastfeeding
- you are using other products containing citrus oils
- you are exposed to sunlight after application
✕ Avoid If:
- you have a known allergy to citrus fruits
- you are using it in high concentrations
- you experience irritation or adverse reactions
- you are taking medications that increase sensitivity to sunlight
Chemical Properties
| Property | Value |
|---|---|
| Solubility | soluble in alcohol and oils |
Common Use Cases
4 Categories
Cosmetic
Facial creams, perfumes, soaps. Dilute before use to minimize skin irritation.
Food
Flavoring agents, beverages, confectionery. Generally safe in small amounts; check for allergies.
Pharmaceutical
Topical ointments, aromatherapy oils. Use with caution; consult a healthcare provider.
Supplement
Dietary supplements, herbal teas. Consult a healthcare professional before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Citrus Aurantium Bergamia Peel Oil is generally safe for skin contact but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Citrus Aurantium Bergamia Peel Oil can lead to gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation of the oil may cause respiratory irritation in sensitive individuals, but is generally well tolerated.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and discomfort; caution is advised.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of irritation and allergic reactions.
- pregnant — Potential hormonal effects; limited safety data.
- sensitive_skin — Increased likelihood of skin irritation.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
- breastfeeding — Generally safe with caution; limited data.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults; however, individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; potential hormonal effects are a concern. |
| infants_children | High | Higher sensitivity to essential oils; risk of irritation and allergic reactions. |
| breastfeeding | Low to Moderate | Limited data on effects during breastfeeding; caution is advised. |
| sensitive_skin | High | Individuals with sensitive skin may experience irritation or allergic reactions. |
Toxicology Data
3 Endpoints
Citrus Aurantium Bergamia Peel Oil has been assessed for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | No significant irritation observed | CIR Safety Assessment (2012) |
| Sensitization | not sensitizing | Human patch test | No sensitization observed | CIR Safety Assessment (2012) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Citrus Aurantium Bergamia Peel Oil has been assessed for safety in cosmetics and food applications, showing low toxicity.
- Generally recognized as safe in cosmetics and food.
- May cause skin irritation in sensitive individuals.
- Regulatory assessments support its use in specified concentrations.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Citrus Aurantium Bergamia Peel Oil
Year: 2012
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on the safety of Citrus Aurantium Bergamia
Year: 2015
Conclusion: Considered safe for use as a food flavoring agent.
View Full Report →
FDA
Report: Food Ingredients and Colors
Year: 2021
Conclusion: Generally recognized as safe when used appropriately.
View Full Report →
Regulatory Status
Global
Citrus Aurantium Bergamia Peel Oil is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
Use in cosmetics must comply with safety assessments.
UK
UK GovernmentPERMITTED
Must comply with UK regulations.
CA
Health CanadaPERMITTED
Must comply with safety standards.
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test before use.
Yes, it is generally recognized as safe in food when used in small amounts.
Some individuals may experience skin irritation or allergic reactions; use with caution.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-29T07:01:32.958724Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.