66.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance agent · antimicrobial agent · antioxidant · flavoring agent
Cinnamomum Cassia Leaf Oil
Also known as: Cassia Oil, Cinnamon Leaf Oil
Category
essential oil
Bottom Line: Cinnamomum Cassia Leaf Oil is generally considered safe for use in cosmetics and food, though some individuals may experience sensitivity.
Quick Answer
✔ Generally Safe If:
- used in diluted form in cosmetics
- consumed in small amounts as a flavoring
- not applied to broken skin
- used by adults without known allergies
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or breastfeeding
- you are using other skin irritants
- you have a history of respiratory issues
✕ Avoid If:
- you are allergic to cinnamon or related compounds
- you have liver disease
- you are using it in high concentrations
- you are giving it to children under 2 years
Chemical Properties
| Property | Value |
|---|---|
| Solubility | soluble in alcohol and oils |
Common Use Cases
4 Categories
Cosmetic
Facial creams, essential oil blends, body lotions. Dilute before applying to skin to minimize irritation.
Food
Flavoring agents, baked goods, beverages. Use in moderation as a flavoring agent.
Pharmaceutical
Herbal supplements, topical ointments. Consult a healthcare professional before use.
Supplement
Capsules, liquid extracts. Follow dosage recommendations to avoid adverse effects.
Safety by Route of Exposure
dermal
dermal
Risk Level: Moderate
Cinnamomum Cassia Leaf Oil may cause skin irritation in sensitive individuals.
oral
oral
Risk Level: Low to Moderate
Ingestion can lead to gastrointestinal discomfort; moderation is advised.
inhalation
inhalation
Risk Level: Low
Inhalation of vapors is generally safe but may irritate sensitive airways.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and discomfort.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to essential oils may lead to adverse reactions.
- pregnant — Potential hormonal effects necessitate caution.
- sensitive_skin — Increased risk of irritation and allergic reactions.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with moderate use.
- breastfeeding — Generally safe with caution and monitoring.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low to Moderate | Adults typically tolerate Cinnamomum Cassia Leaf Oil well, but sensitivity varies. |
| pregnant | Moderate | Limited data on safety during pregnancy; potential for hormonal effects. |
| infants_children | High | Children may be more sensitive to essential oils and their effects. |
| breastfeeding | Low to Moderate | Limited data on effects during lactation; caution is advised. |
| sensitive_skin | Very High | Individuals with sensitive skin may experience severe reactions. |
Toxicology Data
3 Endpoints
Cinnamomum Cassia Leaf Oil has been evaluated for safety in cosmetics and food applications, showing potential irritant properties.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | Moderate irritant | Human patch test | Potential for irritation in sensitive individuals | CIR Safety Assessment (2015) |
| Sensitization | Positive in sensitization tests | Human sensitization study | May cause allergic reactions | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Cinnamomum Cassia Leaf Oil has been evaluated for safety in cosmetics and food applications, showing potential irritant properties.
- May cause skin irritation in sensitive individuals.
- Generally recognized as safe in food when used appropriately.
- Limited data on long-term effects in high concentrations.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Cinnamomum Cassia Oil
Year: 2015
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on Cinnamomum Cassia Oil
Year: 2018
Conclusion: Considered safe for use in food as a flavoring agent.
View Full Report →
FDA
Report: Cinnamomum Cassia Leaf Oil Regulatory Status
Year: 2020
Conclusion: Generally recognized as safe when used in food and cosmetics.
View Full Report →
Regulatory Status
Global
Cinnamomum Cassia Leaf Oil is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
It is generally safe when diluted, but some may experience irritation.
Yes, it is safe in small amounts as a flavoring agent in food.
Some individuals may experience skin irritation or allergic reactions.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-29T06:59:23.311533Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.