68.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance agent · flavoring agent · antimicrobial agent · cooling agent
Mentha Viridis Leaf Oil
Also known as: Spearmint Oil, Mentha spicata Oil
Category
essential oil
Bottom Line: Mentha Viridis Leaf Oil is generally considered safe for use in cosmetics and food, though some individuals may experience sensitivity.
Quick Answer
✔ Generally Safe If:
- used in diluted form in cosmetics
- consumed in small amounts as a flavoring agent
- not applied to broken skin
- used by adults without known allergies
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or breastfeeding
- you are using other topical medications
- you have a history of respiratory issues
✕ Avoid If:
- you are allergic to mint or related plants
- you have severe skin conditions
- you are using it in high concentrations
- you are under 2 years old
Chemical Properties
| Property | Value |
|---|---|
| Solubility | soluble in alcohol and oils |
Common Use Cases
4 Categories
Cosmetic
Facial creams, shampoos, body lotions. Use in diluted form to minimize irritation risk.
Food
Mint-flavored candies, beverages, baking extracts. Generally safe in small amounts as a flavoring.
Pharmaceutical
Topical analgesics, cough syrups. Consult a healthcare provider for medicinal use.
Supplement
Digestive aids, essential oil capsules. Use as directed; consult a doctor if unsure.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Mentha Viridis Leaf Oil is generally safe for skin contact but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Low to Moderate
Oral ingestion is typically safe in food amounts, but high doses may lead to gastrointestinal discomfort.
inhalation
inhalation
Risk Level: Low
Inhalation of Mentha Viridis Leaf Oil is generally safe in well-ventilated areas, but may irritate sensitive airways.
ocular
ocular
Risk Level: Moderate
Contact with eyes can cause irritation; caution is advised to avoid exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity and risk of respiratory issues.
✔ Well-Tolerated Groups
- general_adult — Typically well-tolerated with minimal adverse effects.
- breastfeeding — Generally safe in moderate amounts.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well-tolerated in adults; however, individual sensitivities may vary. |
| pregnant | Low to Moderate | Limited data on high doses during pregnancy; use with caution. |
| infants_children | High | Higher sensitivity in young children; potential for respiratory irritation. |
| breastfeeding | Low | Generally considered safe in moderate amounts; monitor for any adverse reactions. |
| sensitive_skin | Moderate | May cause irritation or allergic reactions in individuals with sensitive skin. |
Toxicology Data
3 Endpoints
Mentha Viridis Leaf Oil has been evaluated for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | CIR Safety Assessment (2012) |
| Sensitization | not sensitizing | Human patch test | No sensitization observed | CIR Safety Assessment (2012) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Mentha Viridis Leaf Oil has been evaluated for safety in cosmetics and food applications, showing low toxicity.
- Generally recognized as safe in food applications.
- Low irritation potential in cosmetic use.
- No significant adverse effects reported in studies.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Mentha Viridis Leaf Oil
Year: 2012
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on the safety of Mentha Viridis Leaf Oil
Year: 2018
Conclusion: Considered safe for use in food at specified limits.
View Full Report →
FDA
Report: Food Ingredients and Colors
Year: 2021
Conclusion: Generally recognized as safe when used appropriately.
View Full Report →
Regulatory Status
Global
Mentha Viridis Leaf Oil is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, it may cause irritation in sensitive skin. Always perform a patch test.
Yes, it is generally recognized as safe in food when used in small amounts.
Some individuals may experience allergic reactions or irritation. Use with caution.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-29T07:18:39.697825Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.