66.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance agent · skin conditioning agent · antimicrobial agent · aromatic agent
Pogostemon Cablin Oil
Also known as: Patchouli Oil, Patchouli Essential Oil
Category
essential oil
Bottom Line: Pogostemon Cablin Oil is generally considered safe for use in cosmetics and food, though some individuals may experience sensitivity.
Quick Answer
✔ Generally Safe If:
- used in diluted form for topical applications
- purchased from reputable suppliers
- used in moderation in food products
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or breastfeeding
- you are using other essential oils
✕ Avoid If:
- you have a known allergy to patchouli or related plants
- you are using it in high concentrations
- you are taking medications that may interact
Chemical Properties
| Property | Value |
|---|---|
| Solubility | soluble in alcohol and oils, insoluble in water |
Common Use Cases
4 Categories
Cosmetic
Fragrance oils, skin creams, soaps. Dilute before applying to skin to avoid irritation.
Food
Flavoring agents, herbal teas. Use in moderation as a flavoring agent.
Pharmaceutical
Aromatherapy oils, topical ointments. Consult a healthcare provider before use.
Supplement
Herbal capsules, essential oil blends. Follow dosage recommendations on the label.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Pogostemon Cablin Oil is generally safe for skin contact but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Pogostemon Cablin Oil can cause gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation of the oil may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and discomfort.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to essential oils; potential for adverse reactions.
- sensitive_skin — Increased risk of irritation and allergic reactions.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- elderly — Generally well tolerated, but should monitor for reactions.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; however, individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; use with caution. |
| infants_children | High | Higher sensitivity to essential oils; potential for adverse reactions. |
| breastfeeding | Low to Moderate | Limited data on effects during breastfeeding; use cautiously. |
| elderly | Low | Generally well tolerated, but monitor for any adverse reactions. |
| sensitive_skin | High | Higher risk of irritation and allergic reactions. |
Toxicology Data
3 Endpoints
Pogostemon Cablin Oil has been evaluated for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2012) |
| Skin Irritation | non-irritating | Human patch test | No significant irritation observed | CIR Safety Assessment (2012) |
| Sensitization | possible sensitizer | Human patch test | Caution advised for sensitive individuals | CIR Safety Assessment (2012) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Pogostemon Cablin Oil has been evaluated for safety in cosmetics and food applications, showing low toxicity.
- Generally recognized as safe in diluted forms.
- Potential skin sensitization in sensitive individuals.
- Limited data on long-term effects.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Pogostemon Cablin Oil
Year: 2012
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on Pogostemon Cablin Oil
Year: 2018
Conclusion: Considered safe for use in food flavoring at specified limits.
View Full Report →
FDA
Report: Regulatory Status of Essential Oils
Year: 2020
Conclusion: Generally recognized as safe when used appropriately.
View Full Report →
Regulatory Status
Global
Pogostemon Cablin Oil is generally permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
Use in cosmetics must comply with safety assessments.
UK
UK GovernmentPERMITTED
Must comply with UK regulations.
CA
Health CanadaPERMITTED
Must comply with safety standards.
Frequently Asked Questions
Generally, it is safe when diluted, but perform a patch test first.
It can be used in food flavoring, but moderation is key.
Some individuals may experience skin irritation or allergic reactions.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-29T07:25:13.233017Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.