66.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance agent · antimicrobial agent · antioxidant · flavoring agent
Cinnamomum Zeylanicum Bark Oil
Also known as: Ceylon cinnamon oil, Cinnamon bark oil
Category
essential oil
Bottom Line: Cinnamomum Zeylanicum Bark Oil is generally considered safe for use in cosmetics and food, though it may cause irritation in sensitive individuals.
Quick Answer
✔ Generally Safe If:
- used in diluted form in cosmetics
- consumed in small amounts as a flavoring
- not applied to broken skin
- used by adults without known allergies
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or breastfeeding
- you are taking medications that may interact
- you have a history of skin reactions to essential oils
✕ Avoid If:
- you are allergic to cinnamon or related compounds
- you have a skin condition like eczema
- you are using it in high concentrations
- you are under the age of 2
Chemical Properties
| Property | Value |
|---|---|
| Solubility | soluble in alcohol and oils |
Common Use Cases
4 Categories
Cosmetic
Facial creams, essential oil blends, soaps. Dilute before applying to skin to avoid irritation.
Food
Flavoring agents, baked goods, beverages. Generally safe in small amounts as a flavoring.
Pharmaceutical
Herbal supplements, topical ointments. Consult a healthcare provider before use.
Supplement
Capsules, tinctures. Use under guidance if you have health concerns.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Cinnamomum Zeylanicum Bark Oil is generally safe for skin contact but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Cinnamomum Zeylanicum Bark Oil can be beneficial but may cause gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation of the oil is typically safe, but high concentrations may lead to respiratory irritation.
ocular
ocular
Risk Level: High
Contact with eyes can cause significant irritation and should be avoided.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity and risk of adverse reactions.
- pregnant — Limited safety data; use with caution.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
- elderly — Generally well tolerated, but monitor for sensitivity.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults; however, individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; use with caution. |
| infants_children | High | Higher sensitivity in infants and children; potential for adverse reactions. |
| breastfeeding | Low to Moderate | Limited data on effects during breastfeeding; use cautiously. |
| elderly | Low | Generally well tolerated, but may have increased sensitivity. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Cinnamomum Zeylanicum Bark Oil is recognized for its potential benefits and risks, particularly in cosmetics and food applications.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 18600 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Human patch test | Not a skin irritant | CIR Safety Assessment (2015) |
| Sensitization | no sensitization observed | Human clinical study | Low sensitization potential | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Cinnamomum Zeylanicum Bark Oil is recognized for its potential benefits and risks, particularly in cosmetics and food applications.
- Contains antimicrobial properties.
- May cause skin irritation in sensitive individuals.
- Generally recognized as safe in food applications.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Cinnamomum Zeylanicum Oil
Year: 2015
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on the safety of Cinnamomum Zeylanicum
Year: 2018
Conclusion: Considered safe for use in food at specified levels.
View Full Report →
FDA
Report: Cinnamomum Zeylanicum Bark Oil Regulatory Status
Year: 2020
Conclusion: Generally recognized as safe when used appropriately.
View Full Report →
Regulatory Status
Global
Cinnamomum Zeylanicum Bark Oil is generally permitted across major jurisdictions with no significant restrictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
Generally, it is safe when diluted, but some individuals may experience irritation.
Yes, it is typically safe in small amounts as a flavoring in food.
Some may experience allergic reactions or skin irritation; use with caution.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-29T07:00:23.106344Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.