66.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · flavoring agent · skin conditioning agent · antioxidant
Lippia Citriodora Absolute
Also known as: Lemon Verbena Absolute, Aloysia citriodora
Category
plant extract
Bottom Line: Lippia Citriodora Absolute is generally considered safe for use in cosmetics and food, though individual reactions may vary.
Quick Answer
✔ Generally Safe If:
- used in recommended concentrations
- not applied to broken skin
- not combined with known allergens
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- you are pregnant or breastfeeding
- you are using other topical products
✕ Avoid If:
- you have a known allergy to Lippia species
- you experience irritation or adverse reactions
- you are using it in high concentrations
Chemical Properties
| Property | Value |
|---|---|
| Solubility | soluble in alcohol and oils |
Common Use Cases
3 Categories
Cosmetic
Facial creams, body lotions, shampoos. Generally safe for topical use; patch test recommended.
Food
Herbal teas, flavoring agents, desserts. Generally recognized as safe when used in food applications.
Supplement
Herbal supplements, capsules, extracts. Consult a healthcare provider before use, especially if pregnant.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Lippia Citriodora Absolute is generally safe for skin contact, but may cause irritation in sensitive individuals.
oral
oral
Risk Level: Moderate
Ingestion of Lippia Citriodora Absolute is typically safe in food and supplements, but high doses may cause gastrointestinal upset.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation of the aroma is generally safe, but concentrated forms may irritate respiratory pathways.
ocular
ocular
Risk Level: High
Contact with eyes can cause irritation and discomfort; caution is advised.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity and risk of adverse reactions.
- pregnant — Limited safety data; consult healthcare provider.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risk.
- elderly — Generally safe but should monitor for sensitivities.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults, but individual sensitivities may vary. |
| pregnant | Moderate | Limited data on safety during pregnancy; use with caution. |
| infants_children | High | Higher sensitivity in young children; potential for adverse reactions. |
| breastfeeding | Low to Moderate | Limited data on effects during breastfeeding; use cautiously. |
| elderly | Low | Generally well tolerated, but monitor for sensitivities. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
Lippia Citriodora Absolute is used in cosmetics and food, with some evidence supporting its safety.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | Not available | Insufficient data | CIR Safety Assessment (2015) |
| Skin Irritation | Non-irritating | Human patch test | Low concern for irritation | SCCS Opinion (2020) |
| Sensitization | No sensitization observed | Human clinical study | Low concern for sensitization | EFSA Opinion (2018) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Lippia Citriodora Absolute is used in cosmetics and food, with some evidence supporting its safety.
- Used for its fragrance and potential health benefits.
- Limited studies on long-term safety.
- Generally recognized as safe in food applications.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Lippia Citriodora
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 5%.
View Full Report →
EFSA
Report: Scientific Opinion on Lippia Citriodora
Year: 2018
Conclusion: Considered safe for use in food products.
View Full Report →
SCCS
Report: Opinion on Lippia Citriodora in Cosmetics
Year: 2020
Conclusion: No safety concerns at recommended use levels.
View Full Report →
Regulatory Status
Global
Lippia Citriodora Absolute is permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionPERMITTED
None
UK
UK GovernmentPERMITTED
None
CA
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should patch test before use.
Yes, it is generally recognized as safe for use in food applications.
Some individuals may experience allergic reactions; discontinue use if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-29T07:16:21.113866Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.