8.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · solvent · flavoring agent · stabilizer
4-Methyl-3-Decen-5-Ol
Molecular Formula
C11H22O
Molecular Weight
170.29 g/mol
Category
chemical compound
Bottom Line: 4-Methyl-3-Decen-5-Ol is generally considered safe in cosmetics and food, though its effects can vary based on concentration and individual sensitivity.
Quick Answer
✔ Generally Safe If:
- Used in low concentrations in cosmetic formulations
- Ingested as part of food products within regulatory limits
- No known allergies to similar compounds
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using in combination with other active ingredients
- Pregnant or breastfeeding
✕ Avoid If:
- You have a known allergy to this compound
- Using on broken or irritated skin
- Ingesting in large quantities outside of food products
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C11H22O |
| Molecular Weight | 170.29 g/mol |
| Log P | 3.8 |
Common Use Cases
4 Categories
Cosmetic
Fragrances, skin creams, hair products. Generally safe in cosmetic products when used as directed.
Food
Flavoring agents, beverages. Safe for consumption within established limits.
Pharmaceutical
Topical medications, oral formulations. Use with caution in sensitive populations.
Supplement
Dietary supplements, herbal products. Consult a healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to 4-Methyl-3-Decen-5-Ol is generally well tolerated with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of 4-Methyl-3-Decen-5-Ol may pose moderate risks, including gastrointestinal irritation.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk but may cause respiratory irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Eye contact with 4-Methyl-3-Decen-5-Ol can cause significant irritation and should be avoided.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures may lead to adverse effects.
- pregnant — Limited data necessitates caution during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal adverse effects.
- elderly — Generally tolerate exposure without significant issues.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally healthy adults can tolerate exposure with minimal effects. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; caution is recommended. |
| elderly | Low | Elderly individuals generally tolerate exposure well. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
4-Methyl-3-Decen-5-Ol has been evaluated for safety in cosmetics and food, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Rabbit - Draize test | No significant irritation observed | CIR Safety Assessment (2015) |
| Sensitization | non-sensitizing | Guinea Pig - Maximization test | No sensitization observed | CIR Safety Assessment (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
4-Methyl-3-Decen-5-Ol has been evaluated for safety in cosmetics and food, showing low toxicity.
- Low acute toxicity in animal studies
- Generally recognized as safe in food applications
- Limited skin irritation potential
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of 4-Methyl-3-Decen-5-Ol
Year: 2015
Conclusion: Safe for use in cosmetics at concentrations up to 1%
View Full Report →
EFSA
Report: Scientific Opinion on 4-Methyl-3-Decen-5-Ol
Year: 2018
Conclusion: Considered safe for use as a food flavoring agent
View Full Report →
FDA
Report: Food Additive Status
Year: 2020
Conclusion: Permitted for use in food products under specific conditions
View Full Report →
Regulatory Status
Global
4-Methyl-3-Decen-5-Ol is generally permitted for use in cosmetics and food across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
Use within established limits
European Union
European CommissionPERMITTED
Use in food flavoring only
United Kingdom
UK GovernmentPERMITTED
Use in cosmetics and food
Canada
Health CanadaPERMITTED
Use within established limits
Frequently Asked Questions
Generally, it is safe for skin use in cosmetics, though individuals with sensitive skin should exercise caution.
Yes, it is permitted in food products, but should be consumed within regulatory limits.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T03:34:25.657796Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.