7.0
ISS Score
A- — Good — low to minimal hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
solvent · plasticizer · intermediate · stabilizer
Cyclooctenyl Methyl Carbonate
Molecular Formula
C10H16O3
Molecular Weight
184.23 g/mol
Category
chemical compound
Bottom Line: Cyclooctenyl Methyl Carbonate is generally considered safe for use in cosmetics and household products, though caution is advised for sensitive skin.
Quick Answer
✔ Generally Safe If:
- used in concentrations below 1%
- applied to intact skin
- formulated in products with stabilizers
⚠ Use with Awareness If:
- you have sensitive skin or allergies
- using in combination with other active ingredients
- applying to broken or irritated skin
✕ Avoid If:
- you are pregnant or nursing
- you have a known allergy to similar compounds
- using on children without prior consultation
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C10H16O3 |
| Molecular Weight | 184.23 g/mol |
| Log P | 2.8 |
Common Use Cases
3 Categories
Cosmetic
Facial creams, sunscreens, hair styling products. Use in moderation and perform patch tests.
Pharmaceutical
Topical ointments, transdermal patches. Consult a healthcare provider before use.
Household
Cleaning sprays, air fresheners. Ensure good ventilation when using products.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Cyclooctenyl Methyl Carbonate is generally well tolerated on skin, with low irritation potential.
oral
oral
Risk Level: Insufficient Data
Limited data on oral toxicity; ingestion should be avoided.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure may cause mild respiratory irritation; use in well-ventilated areas.
ocular
ocular
Risk Level: Moderate
Contact with eyes may cause irritation; avoid direct exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited data on safety during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with low irritation potential.
- elderly — Generally well tolerated, but monitor for sensitivity.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Adults typically have a higher tolerance for cosmetic ingredients. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; exercise caution. |
| elderly | Low | Elderly individuals may have varying sensitivities. |
Toxicology Data
3 Endpoints
Cyclooctenyl Methyl Carbonate has limited safety data, primarily used in cosmetics and household products.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | non-irritating | Human patch test | Low irritation potential | CIR Safety Assessment (2021) |
| Sensitization | non-sensitizing | Human patch test | Low sensitization potential | SCCS Opinion (2022) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Cyclooctenyl Methyl Carbonate has limited safety data, primarily used in cosmetics and household products.
- Limited studies on skin irritation and sensitization.
- Generally recognized as safe in low concentrations.
- Further research needed for long-term effects.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Cyclooctenyl Methyl Carbonate
Year: 2021
Conclusion: Safe for use in cosmetics at concentrations up to 1%.
View Full Report →
SCCS
Report: Opinion on Cyclooctenyl Methyl Carbonate
Year: 2022
Conclusion: Insufficient data for full safety evaluation.
View Full Report →
FDA
Report: Regulatory Status of Cyclooctenyl Methyl Carbonate
Year: 2023
Conclusion: No specific regulations; generally recognized as safe.
View Full Report →
Regulatory Status
Global
Cyclooctenyl Methyl Carbonate is permitted in the US and UK, under review in the EU, with no specific regulations in Canada. Switch to Detailed mode for full regulatory breakdown.
US
FDAPERMITTED
None
EU
European CommissionUNDER REVIEW
Pending further studies
UK
UK GovernmentPERMITTED
None
CA
Health CanadaNO_DATA
No specific regulations identified
Frequently Asked Questions
It may cause irritation for some; patch testing is recommended before use.
It's best to avoid using products with this ingredient during pregnancy.
It is often found in facial creams, sunscreens, and household cleaners.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T05:00:55.021786Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.