56.0
ISS Score
Moderate — Score based on regulatory approval status in 4 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
fragrance ingredient · skin conditioning agent · antioxidant · preservative · stabilizer
EVERNIA, EXT.
Category
natural extract
Bottom Line: Generally considered safe for topical use, though some individuals may experience sensitivity. Always patch test products containing Evernia.
Quick Answer
✔ Generally Safe If:
- Used in diluted forms in cosmetic products
- Applied to intact skin
- No known allergies to Evernia or related compounds
⚠ Use with Awareness If:
- You have sensitive skin or allergies
- Using multiple products containing Evernia
- Pregnant or breastfeeding, consult a healthcare provider
✕ Avoid If:
- You have a known allergy to lichens
- Skin is broken or irritated
- Using on children without consulting a pediatrician
Chemical Properties
| Property | Value |
|---|
Common Use Cases
4 Categories
Cosmetic
Fragrances, soaps, lotions. Generally safe for topical use; patch test recommended.
Food
Flavoring agents, herbal teas. Consult with a healthcare provider before use.
Pharmaceutical
Topical ointments, creams. Use under medical supervision if sensitive.
Supplement
Herbal supplements. Consult a healthcare provider before use.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Evernial extract is generally well tolerated on skin, with low irritation potential.
oral
oral
Risk Level: Moderate
Ingestion of Evernia extract may cause mild gastrointestinal discomfort in some individuals.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low risk, but may cause irritation in sensitive individuals.
ocular
ocular
Risk Level: High
Contact with eyes may cause irritation; caution is advised to avoid exposure.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher risk of irritation and allergic reactions.
- pregnant — Limited safety data; use with caution.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with low risk.
- elderly — Generally safe; monitor for adverse effects.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated; monitor for any allergic reactions. |
| pregnant | Moderate | Limited data on safety during pregnancy; use with caution. |
| infants_children | High | Higher sensitivity to potential allergens; risk of irritation. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use cautiously. |
| elderly | Low | Generally well tolerated; monitor for any adverse effects. |
Toxicology Data
3 Endpoints
Evernia is generally recognized as safe for topical use, though some may experience allergic reactions.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Non-irritating | Human patch test | Low irritation potential | CIR Safety Assessment (2012) |
| Sensitization | Potential sensitizer | Human patch test | Moderate concern for sensitive individuals | SCCS Opinion (2015) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Evernia is generally recognized as safe for topical use, though some may experience allergic reactions.
- Derived from lichen, commonly used in cosmetics.
- Potential for skin irritation in sensitive individuals.
- Regulatory assessments indicate moderate safety.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Evernia Prunastri
Year: 2012
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
SCCS
Report: Opinion on Evernia Prunastri
Year: 2015
Conclusion: Considered safe for cosmetic use with restrictions.
View Full Report →
EFSA
Report: Scientific Opinion on the Safety of Evernia Prunastri
Year: 2018
Conclusion: Safe for food use within specified limits.
View Full Report →
Regulatory Status
Global
Evernia is generally permitted in cosmetics and food, with some restrictions in the EU. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionRESTRICTED
Limited use in cosmetics
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin may experience irritation. Patch testing is advised.
Consult a healthcare provider before using products containing Evernia if pregnant or breastfeeding.
Discontinue use immediately and consult a healthcare professional if you experience any adverse reactions.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-19T19:05:14.796386Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.