47.0
ISS Score
Poor — Score based on regulatory approval status in 2 jurisdiction(s), route-level risk assessment across multiple routes, and 3 toxicology endpoints from safety assessments.
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
antioxidant · anti-inflammatory · skin conditioning · fragrance
BULNESIA SARMIENTI, EXT., ACETATE
Category
plant extract
Bottom Line: Generally, Bulnesia sarmienti extract is considered safe for use in cosmetics and food, though individual reactions may vary.
Quick Answer
✔ Generally Safe If:
- Used in recommended concentrations
- Not applied to broken skin
- No known allergies to the ingredient
⚠ Use with Awareness If:
- You have sensitive skin
- You are pregnant or nursing
- You are using other active ingredients
✕ Avoid If:
- You have a known allergy to Bulnesia sarmienti
- You experience irritation or adverse reactions
- You are using on children without consulting a doctor
Chemical Properties
| Property | Value |
|---|
Common Use Cases
4 Categories
Cosmetic
Fragrances, moisturizers, lotions. Generally safe for topical use; patch test recommended.
Food
Flavoring agents, natural extracts. Use in moderation; check for allergies.
Pharmaceutical
Herbal supplements, topical ointments. Consult a healthcare provider before use.
Supplement
Dietary supplements, herbal teas. Follow dosage instructions; monitor for side effects.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Bulnesia sarmienti extract is generally considered low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of Bulnesia sarmienti extract may pose moderate risks, particularly in high doses.
inhalation
inhalation
Risk Level: Insufficient Data
Limited data exists on the inhalation safety of Bulnesia sarmienti extract.
ocular
ocular
Risk Level: Low to Moderate
Eye contact with Bulnesia sarmienti extract may cause mild irritation but is typically low to moderate risk.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity and risk of adverse effects.
- pregnant — Limited safety data; caution advised.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated with minimal risks.
- elderly — Generally well tolerated, but monitor for sensitivity.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults, but individual sensitivities may vary. |
| pregnant | Moderate | Limited studies on safety during pregnancy; caution is advised. |
| infants_children | High | Higher sensitivity in infants and children; potential for adverse effects. |
| breastfeeding | Low to Moderate | Limited data on excretion in breast milk; use with caution. |
| elderly | Low | Generally well tolerated, but may have increased sensitivity. |
Toxicology Data
3 Endpoints
Bulnesia sarmienti extract has been evaluated for safety in cosmetics and food applications, showing low toxicity.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | Not established | — | Insufficient data | — |
| Skin Irritation | Non-irritating | Human patch test | Low irritation potential | CIR Safety Assessment (2020) |
| Sensitization | Not sensitizing | Human clinical study | Low sensitization potential | CIR Safety Assessment (2020) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
Bulnesia sarmienti extract has been evaluated for safety in cosmetics and food applications, showing low toxicity.
- Generally recognized as safe in cosmetics.
- Limited data on food safety, but used in flavoring.
- Potential skin benefits noted in some studies.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of Bulnesia sarmienti
Year: 2020
Conclusion: Safe for use in cosmetics at recommended concentrations.
View Full Report →
EFSA
Report: Scientific Opinion on Bulnesia sarmienti
Year: 2019
Conclusion: Insufficient data to fully assess food safety.
View Full Report →
FDA
Report: Food Ingredients and Colors
Year: 2021
Conclusion: No specific regulations; generally recognized as safe.
View Full Report →
Regulatory Status
Global
Bulnesia sarmienti is generally recognized as safe in the US, with ongoing reviews in the EU. Switch to Detailed mode for full regulatory breakdown.
US
FDAGENERALLY RECOGNIZED AS SAFE
None
EU
European CommissionUNDER REVIEW FOR FOOD USE
Pending further studies
UK
UK GovernmentNO SPECIFIC REGULATIONS
None
CA
Health CanadaNO SPECIFIC REGULATIONS
None
Frequently Asked Questions
While generally safe, individuals with sensitive skin should perform a patch test.
It is used as a flavoring agent, but check for local regulations and allergies.
Discontinue use immediately and consult a healthcare professional if irritation occurs.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-19T18:28:23.211537Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.