Fragrance Notes
CA Perfume
Palermo
Inspired by Byredo · Format: EDP Spray
Safe for everyday use. This product is suitable for most adults in normal fragrance application.
Why This Score
Scores are calculated by HumanSafe™ — an independent third-party platform — using peer-reviewed toxicology sources, regulatory databases, and HumanSafe's Mood Architecture™.
Safety at a Glance
✅ Safe for
- —Daily topical use
- —Most healthy adults
- —Long-term skin contact
- —EDP leave-on format
⚠ Use with care if
- —Sensitive or reactive skin
- —Direct eye-area contact
✕ Avoid if
- —Broken or compromised skin
- —Children under 3 years
Full breakdown available to members. Join free →
Key Factors
Score DriversIngredients
29 Total| CAS No. | INCI Name | FUNCTION | ISS | Status |
|---|---|---|---|---|
| 64-17-5 | Ethanol | Solvent / Carrier | 7.0Poor | Moderate |
| 7732-18-5 | Aqua | Solvent / Carrier | 10.0 | Low Risk |
| 1222-05-5 | Ambroxan | Fragrance ingredient | 7.0A- | Moderate |
| 5989-27-5 | Limonene | Fragrance ingredient | 7.0C | Moderate |
| 106-02-5 | Oxacyclohexadecan-2-One | Fragrance ingredient | 6.6Moderate | Moderate |
24 more ingredients in this formulation
See Full Ingredient List — Join Free →Ingredients sourced from MG Safety Data Sheet and EU Allergen Certificate. Formulation: fragrance oil 20% + Ethanol 65% + Aqua 15%. ⚑ = EU regulated allergen (Regulation EC 1223/2009). Note 1 = Annex II prohibited substance. Note 2 = commercial quality (includes both isomers).
Fragrance Mood Profile
MEI™ Mood ArchitectureIndex™
MEI™ scores are calculated by HumanSafe™ using HumanSafe's Mood Architecture™ — a 9-dimension olfactory-emotion mapping system. MEI is an intensity scale: 3/10 = subtle, 9/10 = immersive. Score reflects mood character, not safety.
Usage & Safety Guidance
Safer Alternatives
Higher PSS ScoreProducts with higher Product Safety Scores. Independently assessed by HumanSafe™.
Frequently Asked Questions
Is Palermo safe for daily use?+
Yes, for most people. The PSS Grade A- score reflects a well-formulated fragrance suitable for regular wear. However, if you have sensitive skin or a history of fragrance allergies, perform a 24-hour patch test on your inner wrist before daily application. If irritation develops, discontinue use.
Are there any ingredients I should watch out for?+
D-LIMONENE is the primary ingredient to monitor. While common in citrus fragrances, it can cause contact dermatitis or allergic reactions in sensitive individuals. AMBROXAN and the other synthetic components score well on safety indices. If you've reacted to citrus fragrances before, consult a dermatologist before using Palermo.
What does a PSS of 7.1/10 (Grade A-) mean?+
The PSS (Product Safety Score) is an independent safety rating where A- indicates above-average safety and tolerability. A score of 7.1/10 suggests the product has passed rigorous ingredient assessment and is suitable for consumer use, though no fragrance is risk-free for all individuals. Those with sensitivities should still exercise caution.
The HumanSafe™ Difference
Most safety tools rate ingredients in isolation — one score regardless of concentration, context, or how the product is used. We assess at actual use concentration.
| Dimension | Other Apps (EWG, Yuka) | HumanSafe™ |
|---|---|---|
| Dose awareness | Same score regardless of concentration | Assessed at actual use concentration in this product |
| Exposure context | Same score for rinse-off and leave-on products | Adjusted for product format and absorption rate |
| Allergens | Binary flag — present or absent | Concentration compared to IFRA/EU safe limits |
| Purchase signal | Score only, no recommendation | Clear verdict + safer alternatives ranked by PSS |
Version & Audit Trail
| Version | Date | PSS Score | ISS (avg) | Change Summary |
|---|---|---|---|---|
| v2.1.0 | April 2026 | 7.4 | — | Current assessment — PSS v4.1 route-weighted engine. Dose-aware scoring at actual use concentration. |




