L'eau De Issara Mikai Pure
EDP Spray

Fragrance Notes

AmbergrisBergamotCashmeranHoneyJasmineLilyMuskOrange BlossomPearPeonyRoseSandalwood
WomenEau de ParfumFloral

CA Perfume

L'eau De Issara Mikai Pure

Inspired by Issey Miyake · Format: EDP Spray

Format
A-
HumanSafe Verified
36 Ingredients Assessed
Generally Safe
74th percentile · No allergens flagged

Safe for everyday use. This product is suitable for most adults in normal fragrance application.

No Banned SubstancesEDP Leave-On Format
Product Safety Score
7.4 / 10
PSSDose-aware safety at actual concentration
Mood Elevation Index™
7.3 / 10
MEI™Romantic mood profile
Environmental Safety
ESSEnvironmental assessment
Evidence Quality
CSSConfidence in evidence base

Why This Score

Benzyl Salicylate is the primary component at high concentration (37.5% combined) with strong safety grades (A and A), indicating well-established dermatological tolerance in fragrances.
Ambroxan, at 20.0% concentration with a grade A rating, is a synthetic fragrance fixative with a long history of safe use in eau de parfum formulations.
Contains multiple salicylate compounds (Benzyl Salicylate and cis-3-Hexenyl Salicylate). While safety grades are A to B, individuals with known salicylate sensitivity should perform a patch test before full application.

Scores are calculated by HumanSafe™ — an independent third-party platform — using peer-reviewed toxicology sources, regulatory databases, and HumanSafe's Mood Architecture™.

Safety at a Glance

✅ Safe for

  • Daily topical use
  • Most healthy adults
  • Long-term skin contact
  • EDP leave-on format

⚠ Use with care if

  • Sensitive or reactive skin
  • Direct eye-area contact

✕ Avoid if

  • Broken or compromised skin
  • Children under 3 years
Bottom line: L'eau D'issey Pure is an eau de parfum with a PSS Grade A- rating (7.0/10), indicating above-average safety. The main concern is the relatively high combined concentration of salicylate-based ingredients; sensitive individuals should patch-test first.

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Key Factors

Score Drivers
01 / INGREDIENT SAFETY
Formulation Quality
Dose-aware ingredient safety at actual use concentration. 25 ingredients assessed using SCCS opinions, ECHA REACH dossiers, and primary literature.
PSS 7.4
02 / ENVIRONMENTAL
Environmental Safety
Environmental impact at full formulation level — sourcing, biodegradability, and persistence in aquatic systems assessed per REACH and ECHA criteria.
Members only
03 / EVIDENCE QUALITY
Data Confidence
Confidence Substantiation Score — weighted evidence quality from clinical RCTs (A), observational studies (B), expert consensus (C). Higher CSS = more reliable scores.
Members only

Ingredients

36 Total
CAS No.INCI NameFUNCTIONISSStatus
64-17-5EthanolSolvent / Carrier7.0PoorModerate
7732-18-5AquaSolvent / Carrier10.0Low Risk
118-58-1Benzyl SalicylateFragrance ingredient9.0A⚑ EU Allergen
1222-05-5AmbroxanFragrance ingredient7.0A-Moderate
65405-77-8Hexenyl SalicylateFragrance ingredient5.6ModerateHigh Concern

31 more ingredients in this formulation

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Ingredients sourced from MG Safety Data Sheet and EU Allergen Certificate. Formulation: fragrance oil 20% + Ethanol 65% + Aqua 15%. ⚑ = EU regulated allergen (Regulation EC 1223/2009). Note 1 = Annex II prohibited substance. Note 2 = commercial quality (includes both isomers).

Fragrance Mood Profile

MEI™ Mood Architecture
Mood Elevation
Index™
7.3
MEI™
Primary Mood
Romantic
Secondary Mood
Confident
Inner Voice
I am beautiful.
CONFIDENCE
6.9
MOOD LIFT
7.7
WARMTH
7.9
ENERGY
3.8
PRESENCE
7.6
IDENTITY
7.2
SOCIAL EASE
7.2

MEI™ scores are calculated by HumanSafe™ using HumanSafe's Mood Architecture™ — a 9-dimension olfactory-emotion mapping system. MEI is an intensity scale: 3/10 = subtle, 9/10 = immersive. Score reflects mood character, not safety.

Usage & Safety Guidance

How to Use
Apply to pulse points — wrists, neck, inner elbow. For Duo Set: oil first, then EDP spray over for superior fixation.
Frequency
Safe for daily use at normal application volumes for healthy adults.
Storage
Room temperature, away from sunlight. Shelf life: 24 months unopened, 12 months after first use.
When to Avoid
Known fragrance allergy. Broken or irritated skin. Children under 3 years.

Safer Alternatives

Higher PSS Score

Products with higher Product Safety Scores. Independently assessed by HumanSafe™.

Frequently Asked Questions

Is L'eau D'issey Pure safe for daily use?+

For most consumers, yes. The product carries a Grade A- PSS score, suggesting it is safe for regular fragrance application. However, daily use should follow standard fragrance guidelines: apply to pulse points (wrists, neck) rather than large body areas, and discontinue if irritation develops. Those with sensitive skin or known fragrance allergies should start with limited application.

Are there any ingredients I should watch out for?+

The formulation is dominated by Benzyl Salicylate (37.5% total), a common fragrance ingredient generally recognized as safe. However, individuals with salicylate sensitivity or aspirin allergy should be cautious, as salicylates can trigger reactions in sensitive populations. The remaining ingredients (Ambroxan and cis-3-Hexenyl Salicylate) are also widely used, but a patch test is recommended if you have a history of fragrance reactions.

What does a PSS of 7.0/10 (Grade A-) mean?+

The PSS (Product Safety Score) is an independent safety assessment tool. A score of 7.0/10 with Grade A- indicates above-average safety relative to similar fragrances, meaning the ingredient profile and concentrations pose low to moderate risk for the general population. This does not guarantee zero adverse effects for all individuals; personal tolerance varies based on skin sensitivity and medical history.

The HumanSafe™ Difference

Most safety tools rate ingredients in isolation — one score regardless of concentration, context, or how the product is used. We assess at actual use concentration.

DimensionOther Apps (EWG, Yuka)HumanSafe™
Dose awarenessSame score regardless of concentrationAssessed at actual use concentration in this product
Exposure contextSame score for rinse-off and leave-on productsAdjusted for product format and absorption rate
AllergensBinary flag — present or absentConcentration compared to IFRA/EU safe limits
Purchase signalScore only, no recommendationClear verdict + safer alternatives ranked by PSS

Version & Audit Trail

Last Updated
April 2026
Scoring Model
PSS v4.1
Data Pipeline
v3.3.2
Status
✓ Verified
VersionDatePSS ScoreISS (avg)Change Summary
v2.1.0April 20267.4Current assessment — PSS v4.1 route-weighted engine. Dose-aware scoring at actual use concentration.
Safety Documents
Safety Data Sheet — EDPCA PS 0279
Available
Download PDF
Safety Data Sheet — OilCA PO 0279
Available
Download PDF
IFRA CertificateCA-0279
Available
Download PDF
Allergen Declaration — EDPCA PS 0279
Available
Download PDF
Allergen Declaration — OilCA PO 0279
Available
Download PDF
Safety Data Sheets are prepared by EMRA LLC for CA Perfume, based on the supplier safety data sheet on file for each fragrance. IFRA and Allergen certificates are original supplier documents on file.
HumanSafe™ is an independent third-party platform. This evaluation is not affiliated with the brand or manufacturer. Scores reflect HumanSafe's proprietary PSS methodology — Ingredient Safety (ISS), Environmental Safety (ESS), and Confidence Substantiation (CSS) — and HumanSafe's Mood Elevation Index™ (MEI™). All scores on a 0–10 display scale. Evidence grades: A=RCT · B=Observational · C=Expert consensus.