Rare Molecules 02
EDP Spray

Fragrance Notes

Ambroxan
Women & MenEau de ParfumAmber

CA Perfume

Rare Molecules 02

Inspired by Escentric Molecules · Format: EDP Spray

Format
A-
HumanSafe Verified
6 Ingredients Assessed
Generally Safe
74th percentile · No allergens flagged

Safe for everyday use. This product is suitable for most adults in normal fragrance application.

No Banned SubstancesEDP Leave-On Format
Product Safety Score
7.4 / 10
PSSDose-aware safety at actual concentration
Mood Elevation Index™
4.0 / 10
MEI™Magnetic mood profile
Environmental Safety
ESSEnvironmental assessment
Evidence Quality
CSSConfidence in evidence base

Why This Score

Coumarin (5.0%) is a well-established fragrance ingredient with a strong safety profile (ISS 7.5/10, Grade A) and a long history of use in consumer products.
Water comprises a significant portion of the formulation (ISS 10.0/10), which helps dilute concentrated fragrance compounds and reduce skin irritation risk.
The two tert-butylcyclohexyloxy alcohol derivatives (totaling 13.7%) are synthetic compounds with moderate-to-good safety grades, but limited published dermatological data exists for these specific ingredients; patch testing is recommended for sensitive skin.

Scores are calculated by HumanSafe™ — an independent third-party platform — using peer-reviewed toxicology sources, regulatory databases, and HumanSafe's Mood Architecture™.

Safety at a Glance

✅ Safe for

  • Daily topical use
  • Most healthy adults
  • Long-term skin contact
  • EDP leave-on format

⚠ Use with care if

  • Sensitive or reactive skin
  • Direct eye-area contact

✕ Avoid if

  • Broken or compromised skin
  • Children under 3 years
Bottom line: Molecules 02 is an Eau de Parfum with a Grade B safety score (PSS 6.0/10), suitable for most adult users. The primary concern is the high concentration of synthetic alcohol derivatives; individuals with sensitive or reactive skin should perform a patch test before regular use.

Full breakdown available to members. Join free →

Key Factors

Score Drivers
01 / INGREDIENT SAFETY
Formulation Quality
Dose-aware ingredient safety at actual use concentration. 4 ingredients assessed using SCCS opinions, ECHA REACH dossiers, and primary literature.
PSS 7.4
02 / ENVIRONMENTAL
Environmental Safety
Environmental impact at full formulation level — sourcing, biodegradability, and persistence in aquatic systems assessed per REACH and ECHA criteria.
Members only
03 / EVIDENCE QUALITY
Data Confidence
Confidence Substantiation Score — weighted evidence quality from clinical RCTs (A), observational studies (B), expert consensus (C). Higher CSS = more reliable scores.
Members only

Ingredients

6 Total
CAS No.INCI NameFUNCTIONISSStatus
64-17-5EthanolSolvent / Carrier7.0PoorModerate
7732-18-5AquaSolvent / Carrier10.0Low Risk
139504-68-02-T-ButylcyclohexyloxybutanolFragrance ingredient7.0BModerate
3738-00-9Naphtho[2,1-B]Furan, Dodecahydro-3a,6,6,9a-Fragrance ingredient5.5ModerateHigh Concern
80-54-6Butylphenyl MethylpropionalFragrance ingredient6.0CNote 1 ⚑

1 more ingredients in this formulation

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Ingredients sourced from MG Safety Data Sheet and EU Allergen Certificate. Formulation: fragrance oil 20% + Ethanol 65% + Aqua 15%. ⚑ = EU regulated allergen (Regulation EC 1223/2009). Note 1 = Annex II prohibited substance. Note 2 = commercial quality (includes both isomers).

Fragrance Mood Profile

MEI™ Mood Architecture
Mood Elevation
Index™
4.0
MEI™
Primary Mood
Magnetic
Secondary Mood
Confident
Inner Voice
I am bold.
CONFIDENCE
4.4
MOOD LIFT
4.0
WARMTH
3.6
ENERGY
1.2
PRESENCE
4.8
IDENTITY
4.0
SOCIAL EASE
3.6

MEI™ scores are calculated by HumanSafe™ using HumanSafe's Mood Architecture™ — a 9-dimension olfactory-emotion mapping system. MEI is an intensity scale: 3/10 = subtle, 9/10 = immersive. Score reflects mood character, not safety.

Usage & Safety Guidance

How to Use
Apply to pulse points — wrists, neck, inner elbow. For Duo Set: oil first, then EDP spray over for superior fixation.
Frequency
Safe for daily use at normal application volumes for healthy adults.
Storage
Room temperature, away from sunlight. Shelf life: 24 months unopened, 12 months after first use.
When to Avoid
Known fragrance allergy. Broken or irritated skin. Children under 3 years.

Safer Alternatives

Higher PSS Score

Products with higher Product Safety Scores. Independently assessed by HumanSafe™.

Frequently Asked Questions

Is Molecules 02 safe for daily use?+

For most adults, yes—the PSS Grade B rating indicates acceptable safety for cosmetic use. However, fragrance concentrations in eau de parfum formulas are higher than in lighter formats like eau de cologne, so daily application should be limited to normal amounts (typically 1–2 spritzes). Those with very sensitive skin or fragrance allergies should consult a dermatologist before daily use.

Are there any ingredients I should watch out for?+

The two tert-butylcyclohexyloxy alcohol compounds (making up over 13% of the product) are the main ingredients to monitor. While they carry grades A–B on the ingredient safety scale, they are synthetic compounds with limited published safety data for extended skin contact. Coumarin, the third major ingredient, is well-established and safe. If you have a history of fragrance sensitivity or contact dermatitis, patch test this product on a small area of skin first.

What does a PSS of 6.0/10 (Grade B) mean?+

The Product Safety Score (PSS) evaluates overall formulation safety based on ingredient concentrations and individual safety profiles. A Grade B score (6.0/10) indicates the product meets safety standards for cosmetic use but does not rank in the highest safety tier. It suggests acceptable use for general adult populations, with some caution recommended for sensitive groups. This is a common score for fragrance products containing synthetic actives.

The HumanSafe™ Difference

Most safety tools rate ingredients in isolation — one score regardless of concentration, context, or how the product is used. We assess at actual use concentration.

DimensionOther Apps (EWG, Yuka)HumanSafe™
Dose awarenessSame score regardless of concentrationAssessed at actual use concentration in this product
Exposure contextSame score for rinse-off and leave-on productsAdjusted for product format and absorption rate
AllergensBinary flag — present or absentConcentration compared to IFRA/EU safe limits
Purchase signalScore only, no recommendationClear verdict + safer alternatives ranked by PSS

Version & Audit Trail

Last Updated
April 2026
Scoring Model
PSS v4.1
Data Pipeline
v3.3.2
Status
✓ Verified
VersionDatePSS ScoreISS (avg)Change Summary
v2.1.0April 20267.4Current assessment — PSS v4.1 route-weighted engine. Dose-aware scoring at actual use concentration.
Safety Documents
Safety Data Sheet — EDPCA PS 0632
Available
Download PDF
Safety Data Sheet — OilCA PO 0632
Available
Download PDF
IFRA CertificateCA-0632
Available
Download PDF
Allergen Declaration — EDPCA PS 0632
Available
Download PDF
Allergen Declaration — OilCA PO 0632
Available
Download PDF
Safety Data Sheets are prepared by EMRA LLC for CA Perfume, based on the supplier safety data sheet on file for each fragrance. IFRA and Allergen certificates are original supplier documents on file.
HumanSafe™ is an independent third-party platform. This evaluation is not affiliated with the brand or manufacturer. Scores reflect HumanSafe's proprietary PSS methodology — Ingredient Safety (ISS), Environmental Safety (ESS), and Confidence Substantiation (CSS) — and HumanSafe's Mood Elevation Index™ (MEI™). All scores on a 0–10 display scale. Evidence grades: A=RCT · B=Observational · C=Expert consensus.