Fragrance Notes
CA Perfume
De Los Santos
Inspired by Byredo · Format: EDP Spray
Safe for everyday use. This product is suitable for most adults in normal fragrance application.
Why This Score
Scores are calculated by HumanSafe™ — an independent third-party platform — using peer-reviewed toxicology sources, regulatory databases, and HumanSafe's Mood Architecture™.
Safety at a Glance
✅ Safe for
- —Daily topical use
- —Most healthy adults
- —Long-term skin contact
- —EDP leave-on format
⚠ Use with care if
- —Sensitive or reactive skin
- —Direct eye-area contact
✕ Avoid if
- —Broken or compromised skin
- —Children under 3 years
Full breakdown available to members. Join free →
Key Factors
Score DriversIngredients
19 Total| CAS No. | INCI Name | FUNCTION | ISS | Status |
|---|---|---|---|---|
| 64-17-5 | Ethanol | Solvent / Carrier | 7.0Poor | Moderate |
| 7732-18-5 | Aqua | Solvent / Carrier | 10.0 | Low Risk |
| 54464-57-2 | Tetramethyl Acetyloctahydronaphthalenes | Fragrance ingredient | 7.0B | Moderate |
| 139504-68-0 | 2-T-Butylcyclohexyloxybutanol | Fragrance ingredient | 7.0B | Moderate |
| 1222-05-5 | Ambroxan | Fragrance ingredient | 7.0A- | Moderate |
14 more ingredients in this formulation
See Full Ingredient List — Join Free →Ingredients sourced from MG Safety Data Sheet and EU Allergen Certificate. Formulation: fragrance oil 20% + Ethanol 65% + Aqua 15%. ⚑ = EU regulated allergen (Regulation EC 1223/2009). Note 1 = Annex II prohibited substance. Note 2 = commercial quality (includes both isomers).
Fragrance Mood Profile
MEI™ Mood ArchitectureIndex™
MEI™ scores are calculated by HumanSafe™ using HumanSafe's Mood Architecture™ — a 9-dimension olfactory-emotion mapping system. MEI is an intensity scale: 3/10 = subtle, 9/10 = immersive. Score reflects mood character, not safety.
Usage & Safety Guidance
Safer Alternatives
Higher PSS ScoreProducts with higher Product Safety Scores. Independently assessed by HumanSafe™.
Frequently Asked Questions
Is De Los Santos safe for daily use?+
De Los Santos can be worn daily by most consumers, but its Grade B PSS score indicates moderate—not high—safety assurance. Those with sensitive skin, fragrance allergies, or respiratory conditions should perform a patch test first and consider limiting frequency of use. If irritation or headaches develop, discontinue use.
Are there any ingredients I should watch out for?+
The primary concern is cumulative exposure to synthetic polycyclic fragrance compounds, which make up over half the formula. Ethanone octahydro derivatives are moderately scored (6.6/10) and less documented than some alternatives. If you have a history of fragrance sensitivity or contact dermatitis, consult a dermatologist before use.
What does a PSS of 6.8/10 (Grade B) mean?+
The Product Safety Score (PSS) is an independent safety assessment on a scale of 1–10. Grade B (6.8) indicates moderate safety—the product meets basic safety standards but is not in the highest safety tier. This means it is generally safe for typical consumers but may not be ideal for those with fragrance sensitivities or compromised skin barriers.
The HumanSafe™ Difference
Most safety tools rate ingredients in isolation — one score regardless of concentration, context, or how the product is used. We assess at actual use concentration.
| Dimension | Other Apps (EWG, Yuka) | HumanSafe™ |
|---|---|---|
| Dose awareness | Same score regardless of concentration | Assessed at actual use concentration in this product |
| Exposure context | Same score for rinse-off and leave-on products | Adjusted for product format and absorption rate |
| Allergens | Binary flag — present or absent | Concentration compared to IFRA/EU safe limits |
| Purchase signal | Score only, no recommendation | Clear verdict + safer alternatives ranked by PSS |
Version & Audit Trail
| Version | Date | PSS Score | ISS (avg) | Change Summary |
|---|---|---|---|---|
| v2.1.0 | April 2026 | 7.3 | — | Current assessment — PSS v4.1 route-weighted engine. Dose-aware scoring at actual use concentration. |




