Rare Molecules 01
EDP Spray

Fragrance Notes

Iso E Super
Women & MenEau de ParfumWoody Floral Musk

CA Perfume

Rare Molecules 01

Inspired by Escentric Molecules · Format: EDP Spray

Format
A-
HumanSafe Verified
56 Ingredients Assessed
Generally Safe
70th percentile · No allergens flagged

Safe for everyday use. This product is suitable for most adults in normal fragrance application.

No Banned SubstancesEDP Leave-On Format
Product Safety Score
7.0 / 10
PSSDose-aware safety at actual concentration
Mood Elevation Index™
5.6 / 10
MEI™Magnetic mood profile
Environmental Safety
ESSEnvironmental assessment
Evidence Quality
CSSConfidence in evidence base

Why This Score

Eau de Parfum format is a standard, well-established fragrance delivery system with established safety history in personal care use.
Woody Floral Musk fragrance families are commonly used in consumer products and generally well-tolerated by most users.
The primary ingredient comprises 99.5% of the formulation with a moderate ISS safety score (6.6/10). While not flagged as hazardous, the high concentration of a single ingredient warrants patch testing before widespread use, particularly for sensitive skin.

Scores are calculated by HumanSafe™ — an independent third-party platform — using peer-reviewed toxicology sources, regulatory databases, and HumanSafe's Mood Architecture™.

Safety at a Glance

✅ Safe for

  • Daily topical use
  • Most healthy adults
  • Long-term skin contact
  • EDP leave-on format

⚠ Use with care if

  • Sensitive or reactive skin
  • Direct eye-area contact

✕ Avoid if

  • Broken or compromised skin
  • Children under 3 years
Bottom line: Molecules 01 is an Eau de Parfum with a Grade B PSS rating (6.6/10), indicating moderate overall safety. The primary concern is the very high concentration (99.5%) of a single woody ingredient with moderate safety data; patch testing is recommended before daily use.

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Key Factors

Score Drivers
01 / INGREDIENT SAFETY
Formulation Quality
Dose-aware ingredient safety at actual use concentration. 3 ingredients assessed using SCCS opinions, ECHA REACH dossiers, and primary literature.
PSS 7.0
02 / ENVIRONMENTAL
Environmental Safety
Environmental impact at full formulation level — sourcing, biodegradability, and persistence in aquatic systems assessed per REACH and ECHA criteria.
Members only
03 / EVIDENCE QUALITY
Data Confidence
Confidence Substantiation Score — weighted evidence quality from clinical RCTs (A), observational studies (B), expert consensus (C). Higher CSS = more reliable scores.
Members only

Ingredients

56 Total
CAS No.INCI NameFUNCTIONISSStatus
64-17-5EthanolSolvent / Carrier7.0PoorModerate
7732-18-5AquaSolvent / Carrier10.0Low Risk
127-51-5Methyl IononesFragrance ingredient8.0A⚑ EU Allergen
80-54-6Butylphenyl MethylpropionalFragrance ingredient6.0CNote 1 ⚑
31906-04-4Hydroxyisohexyl-3-Cyclohexene CarboxaldehydeFragrance ingredient5.7ModerateNote 1 ⚑

51 more ingredients in this formulation

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Ingredients sourced from MG Safety Data Sheet and EU Allergen Certificate. Formulation: fragrance oil 20% + Ethanol 65% + Aqua 15%. ⚑ = EU regulated allergen (Regulation EC 1223/2009). Note 1 = Annex II prohibited substance. Note 2 = commercial quality (includes both isomers).

Fragrance Mood Profile

MEI™ Mood Architecture
Mood Elevation
Index™
5.6
MEI™
Primary Mood
Magnetic
Secondary Mood
Confident
Inner Voice
I am bold.
CONFIDENCE
6.6
MOOD LIFT
4.8
WARMTH
5.4
ENERGY
2.4
PRESENCE
7.8
IDENTITY
7.2
SOCIAL EASE
4.2

MEI™ scores are calculated by HumanSafe™ using HumanSafe's Mood Architecture™ — a 9-dimension olfactory-emotion mapping system. MEI is an intensity scale: 3/10 = subtle, 9/10 = immersive. Score reflects mood character, not safety.

Usage & Safety Guidance

How to Use
Apply to pulse points — wrists, neck, inner elbow. For Duo Set: oil first, then EDP spray over for superior fixation.
Frequency
Safe for daily use at normal application volumes for healthy adults.
Storage
Room temperature, away from sunlight. Shelf life: 24 months unopened, 12 months after first use.
When to Avoid
Known fragrance allergy. Broken or irritated skin. Children under 3 years.

Safer Alternatives

Higher PSS Score

Products with higher Product Safety Scores. Independently assessed by HumanSafe™.

Frequently Asked Questions

Is Molecules 01 safe for daily use?+

Molecules 01 carries a Grade B safety rating, which indicates moderate safety for typical use. However, because the formulation is dominated by a single ingredient at 99.5% concentration, a patch test on a small area of skin is recommended before committing to daily application. Some users may experience sensitivity; discontinue use if irritation occurs.

Are there any ingredients I should watch out for?+

The primary ingredient is a synthetic woody compound that makes up virtually the entire formulation. While this ingredient is not listed as a major allergen or hazard, its high concentration is unusual and warrants caution. Individuals with sensitive skin, fragrance sensitivities, or a history of skin reactions should perform a patch test first.

What does a PSS of 6.6/10 (Grade B) mean?+

The PSS (Product Safety Score) of 6.6/10 and Grade B rating indicate moderate safety—the product is not considered high-risk but is not in the highest safety tier either. This grade suggests the product is generally acceptable for consumer use under normal conditions, though users should follow standard fragrance application practices and be aware of individual sensitivities.

The HumanSafe™ Difference

Most safety tools rate ingredients in isolation — one score regardless of concentration, context, or how the product is used. We assess at actual use concentration.

DimensionOther Apps (EWG, Yuka)HumanSafe™
Dose awarenessSame score regardless of concentrationAssessed at actual use concentration in this product
Exposure contextSame score for rinse-off and leave-on productsAdjusted for product format and absorption rate
AllergensBinary flag — present or absentConcentration compared to IFRA/EU safe limits
Purchase signalScore only, no recommendationClear verdict + safer alternatives ranked by PSS

Version & Audit Trail

Last Updated
April 2026
Scoring Model
PSS v4.1
Data Pipeline
v3.3.2
Status
✓ Verified
VersionDatePSS ScoreISS (avg)Change Summary
v2.1.0April 20267.0Current assessment — PSS v4.1 route-weighted engine. Dose-aware scoring at actual use concentration.
Safety Documents
Safety Data Sheet — EDPCA PS 1050
Available
Download PDF
Safety Data Sheet — OilCA PO 1050
Available
Download PDF
IFRA CertificateCA-1050
Available
Download PDF
Allergen Declaration — EDPCA PS 1050
Available
Download PDF
Allergen Declaration — OilCA PO 1050
Available
Download PDF
Safety Data Sheets are prepared by EMRA LLC for CA Perfume, based on the supplier safety data sheet on file for each fragrance. IFRA and Allergen certificates are original supplier documents on file.
HumanSafe™ is an independent third-party platform. This evaluation is not affiliated with the brand or manufacturer. Scores reflect HumanSafe's proprietary PSS methodology — Ingredient Safety (ISS), Environmental Safety (ESS), and Confidence Substantiation (CSS) — and HumanSafe's Mood Elevation Index™ (MEI™). All scores on a 0–10 display scale. Evidence grades: A=RCT · B=Observational · C=Expert consensus.