9.0
ISS Score
A — Good — low hazard
↑ Higher = Safer
Environmental
(ESS)
(ESS)
—
Confidence
(CSS)
(CSS)
—
solvent · emollient · surfactant · humectant
Ppg-2 Methyl Ether
Molecular Formula
C7H16O3
Molecular Weight
148.20 g/mol
Category
chemical compound
Bottom Line: PPG-2 Methyl Ether is generally considered safe in cosmetics and household products, though caution is advised for sensitive skin.
Quick Answer
✔ Generally Safe If:
- used in well-formulated products
- applied to intact skin
- used in recommended concentrations
⚠ Use with Awareness If:
- you have sensitive skin
- you are pregnant or nursing
- you are using other active ingredients
✕ Avoid If:
- you have a known allergy to similar compounds
- you experience irritation or adverse reactions
- you are using on broken skin
Chemical Properties
| Property | Value |
|---|---|
| Molecular Formula | C7H16O3 |
| Molecular Weight | 148.20 g/mol |
| Melting Point | -112.0°C |
| Boiling Point | 408.0°C |
| Solubility | Miscible |
| Log P | -0.1 |
Common Use Cases
3 Categories
Cosmetic
Moisturizers, hair conditioners, makeup removers. Generally safe for topical use; patch test recommended.
Pharmaceutical
Topical creams, ointments. Use as directed; consult a healthcare provider if unsure.
Household
Cleaning agents, air fresheners. Ensure good ventilation during use; avoid ingestion.
Safety by Route of Exposure
dermal
dermal
Risk Level: Low
Dermal exposure to Ppg-2 Methyl Ether is generally considered low risk for skin contact.
oral
oral
Risk Level: Moderate
Ingestion of Ppg-2 Methyl Ether poses moderate risks, with potential gastrointestinal irritation.
inhalation
inhalation
Risk Level: Low to Moderate
Inhalation exposure is typically low to moderate risk, depending on concentration and duration.
ocular
ocular
Risk Level: High
Eye contact with Ppg-2 Methyl Ether can cause significant irritation and should be avoided.
Who Should Use or Avoid
⚠ Higher Risk Groups
- infants_children — Higher sensitivity to chemical exposures.
- pregnant — Limited data; caution advised during pregnancy.
✔ Well-Tolerated Groups
- general_adult — Typically well tolerated in healthy adults.
- elderly — Generally well tolerated, but monitor for sensitivity.
Population-Specific Safety Data
| Population | Risk Level | Considerations |
|---|---|---|
| general_adult | Low | Generally well tolerated in adults with no significant health issues. |
| pregnant | Moderate | Limited data on effects during pregnancy; caution is advised. |
| infants_children | High | Children may be more sensitive to chemical exposures. |
| breastfeeding | Low to Moderate | Limited data on transfer through breast milk; use cautiously. |
| elderly | Low | Generally well tolerated, but monitor for sensitivity. |
| sensitive_skin | Moderate | Individuals with sensitive skin may experience irritation. |
Toxicology Data
3 Endpoints
PPG-2 Methyl Ether is a low-toxicity compound used in various consumer products. Safety assessments indicate it is generally safe when used as intended.
| Endpoint | Value | Test Method | Interpretation | Source |
|---|---|---|---|---|
| LD50 Oral | 5000 mg/kg | Rat - Oral gavage | Low acute toxicity | CIR Safety Assessment (2015) |
| Skin Irritation | non-irritating | Human patch test | No irritation observed | SCCS Opinion (2016) |
| Sensitization | not sensitizing | Human repeated insult patch test | No sensitization observed | FDA Regulatory Review (2021) |
Data Quality: All toxicology values are sourced from verified regulatory assessments (CIR, SCCS, ECHA REACH) following OECD test guidelines. Values are used to calculate the Ingredient Safety Score (ISS).
Scientific Evidence
Key Assessments
PPG-2 Methyl Ether is a low-toxicity compound used in various consumer products. Safety assessments indicate it is generally safe when used as intended.
- Low toxicity profile in cosmetic formulations.
- No significant adverse effects reported in studies.
- Widely used in personal care and household products.
Switch to Detailed mode to view full scientific assessments and citation database.
CIR
Report: Safety Assessment of PPG-2 Methyl Ether
Year: 2015
Conclusion: PPG-2 Methyl Ether is safe for use in cosmetics at concentrations up to 10%.
View Full Report →
SCCS
Report: Opinion on PPG-2 Methyl Ether
Year: 2016
Conclusion: The SCCS considers PPG-2 Methyl Ether safe for use in cosmetic products.
View Full Report →
FDA
Report: Regulatory Status of PPG-2 Methyl Ether
Year: 2021
Conclusion: PPG-2 Methyl Ether is permitted for use in cosmetics and household products.
View Full Report →
Regulatory Status
Global
PPG-2 Methyl Ether is permitted for use in cosmetics and household products across major jurisdictions. Switch to Detailed mode for full regulatory breakdown.
United States
FDAPERMITTED
None
European Union
European CommissionPERMITTED
None
United Kingdom
UK GovernmentPERMITTED
None
Canada
Health CanadaPERMITTED
None
Frequently Asked Questions
While generally safe, those with sensitive skin should perform a patch test before use.
Currently, there is no established safety assessment for food use; caution is advised.
Discontinue use immediately and consult a healthcare professional if irritation persists.
Version History
Audit Trail
| Version | Date | ISS Score | What Changed |
|---|---|---|---|
| 1.0.0 - Initial enrichment | 2026-04-13T07:49:49.153856Z | — | Initial data enrichment via 3-phase structured outputs |
⚠ Important Notice: This information is for educational purposes only and does not constitute medical, professional, or regulatory advice. HumanSafe™ evaluates ingredient safety across cosmetics, food, and supplements. Scores are exposure-route and context-specific. Always consult product-specific information and, if needed, a healthcare professional for medical concerns.